Effect of endometriosis on implantation rates when compared to tubal factor in fresh non donor in vitro fertilization cycles

Neeta Singh, Kusum Lata, Moumita Naha, Neena Malhotra, Abhinash Tiwari, Perumal Vanamail
Journal of human reproductive sciences · 2014 · vol. 7(2) , pp. 143 · doi:10.4103/0974-1208.138874 · PMID:25191029 · PMC4150142 · W1965496487
article OA: gold CC0 ⤵ 36 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Women with endometriosis undergoing IVF had lower oocyte yield and fertilization rates than those with tubal factor infertility, but comparable implantation and pregnancy rates.

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Abstract

OBJECTIVE: The objective of the following study is to compare the outcome of in vitro fertilization and embryo transfer (IVF-ET) in women with endometriosis and tubal-factor infertility. DESIGN: Retrospective study. SETTING: Tertiary referral hospital, assisted reproductive technologies unit. MATERIALS AND METHOD: The study group consisted of 78 women diagnosed with advanced stage endometriosis. The control group included 100 women with tubal-factor infertility. These groups were retrospectively analyzed regarding stimulation, fertilization, embryo development, implantation and pregnancy outcome. INTERVENTION S: Controlled ovarian hyperstimulation and IVF-ET. RESULTS: Lower oocyte yield with lower fertilization rate were found in women with endometriosis compared with tubal-factor control subjects. However, no differences were found in cleavage, implantation and clinical pregnancy rates between the endometriosis and tubal-factor groups. CONCLUSIONS: Our results showed that women with endometriosis have a lower oocyte yield and lower fertilization rate compared with women with tubal-factor infertility. However, once the oocyte is fertilized, it seems that the embryo has a normal chance of implantation, leading to similar pregnancy rates and adequately treated women with endometriosis have equal chances of conception as seen with tubal-factor infertility.

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endometriosisinfertility

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