Reproductive outcomes in women with advanced endometriosis in fresh versus frozen embryo transfer cycles.

A Shoukry, Wael Samir El Gazeirly, Mohamed Abdelkader Khattab, Hesham Mahmoud Adel Abdelmoneim
In: Research Square · 2024 · doi:10.21203/rs.3.rs-4335275/v1 · W4399153995
preprint OA: green CC0
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This study compared reproductive outcomes in women with advanced endometriosis undergoing fresh versus frozen embryo transfer, finding higher implantation and ongoing pregnancy rates with frozen embryo transfers.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This retrospective cohort study compared reproductive outcomes between fresh embryo transfer and freeze-all, deferred frozen embryo transfer after ICSI in women aged 18–37 with laparoscopy-diagnosed advanced endometriosis (r-ASRM stage III/IV) recruited from two IVF centers in Alexandria, Egypt. After excluding women with uterine lesions including adenomyosis and other factors, 211 matched participants (103 fresh; 108 frozen) were analyzed for ongoing pregnancy, implantation, clinical pregnancy, and miscarriage rates. Ongoing pregnancy, implantation, and clinical pregnancy rates were significantly higher in the frozen embryo transfer group, while miscarriage rate was numerically higher after fresh transfer but not statistically significant. The paper’s main limitation is its retrospective design and reliance on medical record review, and it does not report randomized allocation or control for all potential confounders. This paper is centrally about endometriosis — it evaluates how a freeze-all strategy vs fresh embryo transfer affects implantation and ongoing pregnancy outcomes in women with advanced endometriosis.

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Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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