The Effects of Age, Endometriosis, Polycystic Ovarium Syndrome, and Obesity on the Success of Embryo Transfer on In Vitro Fertilization

Background: One of the important stages in in vitro fertilization (IVF) success is the embryo transfer (ET). Many studies are examining the effect of maternal factors on in vitro fertiliza­tion outcomes. However, studies that are only up to the ET stage are still rare. This study aimed to prove whether maternal factors, espe­cially age, endometriosis, PCOS, and obesity, affect ET success in IVF. Subjects and Method: This was an analytic observational study with a case-control design. A sample of 111 patients who undergo IVF at Sekar Fertility Clinic, Dr. Moewardi Surakarta, was selected by total sampling. The dependent variable was the ET success. The independent variables were maternal age, history of endo­metriosis, PCOS, and obesity. The data were analyzed by a multiple logistic regression. Results: The prevalence of ET success in IVF from January 2014 to November 2019 at Sekar Fertility Clinic, Dr. Moewardi, was 65.77% (73 of 111 cycles). Only a history of endometriosis could affect the ET success which was statis­tically significant (aOR= 0.25; 95% CI= 0.08 to 0.78; p= 0.017). ET success was affected by age, PCOS, and obesity, but it was not statistically significant. Conclusion: Endometriosis affects the ET success in IVF, and it is statistically significant. While age, PCOS, and obesity affect the ET success in IVF, but they are not statistically significant. Keywords: embryo transfer, in vitro fertilization, endometriosis, polycystic ovarium syndrome Correspondence: Atthahira Amalia Hafiizha. Faculty of Medicine, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: attha­[email protected]. Journal of Maternal and Child Health (2020), 05(05): 482-489 https://doi.org/10.26911/thejmch.2020.05.05.03.