In vitro fertilization/embryo transfer in unexplained infertility and minimal peritoneal endometriosis
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This retrospective study found similar IVF-ET outcomes, including pregnancy rates, between unexplained infertility and minimal peritoneal endometriosis groups, but lower cleavage rates compared to tubal infertility.
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Abstract
BACKGROUND: To compare the outcome of in vitro fertilization/embryo transfer (IVF-ET) in unexplained infertility and infertility associated with minimal peritoneal endometriosis. METHODS: A retrospective analysis comparing results of stimulation, sperm characteristics, cleavage, implantation and pregnancy rates in patients with unexplained infertility and peritoneal endometriosis associated infertility. Couples with tubal infertility constituted a control group. RESULTS: In the unexplained infertility and endometriosis groups similar response to stimulation, similar sperm characteristics and cleavage rates were observed. Compared with tubal infertility lower sperm motility was seen in the unexplained infertility group. Both non tubal infertility groups had lower cleavage rate than was seen in the control group. No differences in pregnancy rate were observed, but a significantly higher implantation rate was seen in unexplained infertility compared with tubal infertility. CONCLUSIONS: Couples with unexplained infertility and infertility associated with minimal peritoneal endometriosis have similar outcomes in an IVF-ET set up. Significantly lower cleavage rates in these groups compared with tubal infertility indicate gamete defects as possible causes of infertility.
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- Reproductive, obstetric, and perinatal outcomes of women with adenomyosis and endometriosis: a systematic review and meta-analysis 2019
- Hydrosalpinx: Tubal surgery or <i>in vitro</i> fertilisation? An everlasting dilemma nowadays; a narrative review 2017
- Implications of immune dysfunction on endometriosis associated infertility 2016
- <i>In Vitro</i> Fertilization for Endometriosis-Associated Infertility 2015
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- Endometriosis Is Not Associated with Inferior Pregnancy Rates in in vitro Fertilization: An Analysis of 616 Patients 2014
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- Impact of endometriosis and its staging on assisted reproduction outcome: systematic review and meta-analysis 2014
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- Reduced Fecundity in Female Rats with Surgically Induced Endometriosis and in Their Daughters: A Potential Role for Tissue Inhibitors of Metalloproteinase 11 2008
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