In vitro fertilization/embryo transfer in unexplained infertility and minimal peritoneal endometriosis
Observational
OA: closed
CC0
⤵ 47 in-corpus citations
AI-generated summary
This retrospective study found similar IVF-ET outcomes, including pregnancy rates, between unexplained infertility and minimal peritoneal endometriosis groups, but lower cleavage rates compared to tubal infertility.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
BACKGROUND: To compare the outcome of in vitro fertilization/embryo transfer (IVF-ET) in unexplained infertility and infertility associated with minimal peritoneal endometriosis.
METHODS: A retrospective analysis comparing results of stimulation, sperm characteristics, cleavage, implantation and pregnancy rates in patients with unexplained infertility and peritoneal endometriosis associated infertility. Couples with tubal infertility constituted a control group.
RESULTS: In the unexplained infertility and endometriosis groups similar response to stimulation, similar sperm characteristics and cleavage rates were observed. Compared with tubal infertility lower sperm motility was seen in the unexplained infertility group. Both non tubal infertility groups had lower cleavage rate than was seen in the control group. No differences in pregnancy rate were observed, but a significantly higher implantation rate was seen in unexplained infertility compared with tubal infertility.
CONCLUSIONS: Couples with unexplained infertility and infertility associated with minimal peritoneal endometriosis have similar outcomes in an IVF-ET set up. Significantly lower cleavage rates in these groups compared with tubal infertility indicate gamete defects as possible causes of infertility.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood (2-hop)
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]
References (22)
- Assisted fertilization in infertile women with patent fallopian tubes. A comparison of in-vitro fertilization, gamete intra-fallopian transfer and tubal embryo stage transfer via openalex
- Danazol and medroxyprogesterone acetate inefficacious in the treatment of infertility in endometriosis via openalex
- Efficacy of danazol treatment for minimal endometriosis in infertile women. A prospective, randomized study via openalex
- Pathophysiology of mild endometriosis: review of literature via openalex
- Peritoneal fluid in patients with and without endometriosis: prostanoids and macrophages and their effect on the spermatozoa penetration assay via openalex
- Peritoneal fluid prostaglandins in endometriosis, tubal disorders, and unexplained infertility via openalex
- The effect of endometriomas on in vitro fertilization outcome via openalex
- The first attempt at IVF treatment. Results and requirements for a satisfactory success rate via openalex
- The relationship of tubal blockage, infertility of unknown cause, suspected male infertility, and endometriosis to success of in vitro fertilization and embryo transfer via openalex
- The value of in vitro fertilization for the treatment of unexplained infertility via openalex
- W2417297722 via openalex
- W2417970028 via openalex
- W2477008945 via openalex
- W1935541752 via openalex
- W1958921198 via openalex
- W1965034967 via openalex
- W1988368671 via openalex
- W2019931933 via openalex
- W2151973893 via openalex
- W2247717480 via openalex
- W2276863329 via openalex
- W2416140211 via openalex
Cited by (48)
- Beyond the surface: Does stage I-II endometriosis impact fertility? Exploring the challenges of mild disease 2024
- Reproductive, obstetric, and perinatal outcomes of women with adenomyosis and endometriosis: a systematic review and meta-analysis 2019
- Hydrosalpinx: Tubal surgery or in vitro fertilisation? An everlasting dilemma nowadays; a narrative review 2017
- Implications of immune dysfunction on endometriosis associated infertility 2016
- In vitro fertilization for endometriosis-associated infertility 2015
- Influence of endometriosis on assisted reproductive technology outcomes: a systematic review and meta-analysis 2014
- Endometriosis is not associated with inferior pregnancy rates in in vitro fertilization: an analysis of 616 patients 2014
- Effect of endometriosis on implantation rates when compared to tubal factor in fresh non donor in vitro fertilization cycles 2014
- Impact of endometriosis and its staging on assisted reproduction outcome: systematic review and meta-analysis 2014
- Developmental exposure of fetal ovaries and fetal germ cells to endometriosis in an endometriosis model causes differential gene expression in the preimplantation embryos of the first-generation and second-generation embryos 2013
- Minimal and mild endometriosis negatively impact on pregnancy outcome 2012
- Endometriosis and ART 2012
- Cellular and molecular basis for endometriosis-associated infertility 2012
- Minimal and mild endometriosis negatively impact on pregnancy outcome 2012
- Minimal and mild endometriosis negatively impact on pregnancy outcome 2012
- Embryo Quality and Pregnancy Outcome in Infertile Patients with Endometriosis 2012
- In vitro fertilization is a successful treatment in endometriosis-associated infertility 2012
- Implantation Rate Remains Unaffected in Women with Endometriosis Compared to Tubal Factor Infertility 2011
- Infertility Therapies: The Role of Assisted Reproductive Technologies 2011
- [Assisted reproductive technologies place] 2010
- Impact of endometriosis on IVF outcomes 2009
- Reduced fecundity in female rats with surgically induced endometriosis and in their daughters: a potential role for tissue inhibitors of metalloproteinase 1 2008
- Endometriosis, recurrent miscarriage and implantation failure: is there an immunological link? 2006
- Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis 2006
- Increased ENA-78 in the follicular fluid of patients with endometriosis 2006
- Pregnancy outcome after IVF and ICSI in unexplained, endometriosis-associated and tubal factor infertility 2005
- Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis 2004
- Endometriosis and inflammation in infertility 2004
- Endometriosis and inflammation in infertility 2004
- Comparison of fecundity after second laparotomy for endometriosis to in vitro fertilization and embryo transfer 2004
- An evidence-based evaluation of endometriosis-associated infertility 2003
- Fibroblast growth factor (FGF), intracellular adhesion molecule (sICAM-1) level in serum and follicular fluid of infertile women with polycystic ovarian syndrome, endometriosis and tubal damage, and their effect on ICSI outcome 2003
- Effect of endometriosis on in vitro fertilization 2002
- Effect of endometriosis on in vitro fertilization 2002
- Role of laparoscopy in the treatment of endometriosis-associated infertility 2002
- Endometriosis and assisted reproductive technologies: are outcomes affected? 2001
- Natural cycle IVF in unexplained, endometriosis-associated and tubal factor infertility 2001
- Elevated expression of tumour necrosis factor alpha in cultured granulosa cells from women with endometriosis 2000
- Is the endometrium or oocyte/embryo affected in endometriosis? 1999
- Pathophysiology of endometriosis-associated infertility 1999
- The relevance of the peritoneal fluid in endometriosis-associated infertility 1999
- Chapter 7 Endometriosis-associated Infertility and New Reproductive Technologies 1999
- Outcome of IVF in patients with endometriosis in comparison with tubal-factor infertility 1998
- Artificial insemination by husband in unexplained infertility compared with infertility associated with peritoneal endometriosis 1998
- Endometriosis-associated infertility 1997
- Angiogenesis and macrophage activation in endometriosis 1997
- Superovulation combined with insemination or timed intercourse in the treatment of couples with unexplained infertility and minimal endometriosis 1997
- Uterine hyperperistalsis and dysperistalsis as dysfunctions of the mechanism of rapid sperm transport in patients with endometriosis and infertility 1996
Source provenance
- europepmc
- last seen: 2026-10-15T06:08:49.021275+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:58:54.395363+00:00
- unpaywall
- last seen: 2026-10-15T06:24:24.424788+00:00
License: CC0
· commercial use OK