Endometriosis and assisted reproductive technologies: are outcomes affected?

Mahutte NG, Neal Mahutte, N G Mahutte, A Arici, Arici A, Aydın Arıcı
Current opinion in obstetrics & gynecology · 2001 · vol. 13(3) , pp. 275–279 · doi:10.1097/00001703-200106000-00005 · PMID:11396650 · W2047480455
review OA: closed CC0 ⤵ 27 in-corpus citations
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While endometriosis may not affect overall IVF pregnancy rates, it can impair oocyte quality and implantation, suggesting optimized ART protocols might improve outcomes.

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Abstract

The preponderance of recent data suggests that endometriosis does not adversely affect in-vitro fertilization pregnancy rates. However, many studies demonstrate impaired oocyte quality, decreased fertilization, and compromised implantation rates. Such findings give insight into the mechanisms by which endometriosis may impact on fertility, and provide clues as how to focus assisted reproductive technologies in order to overcome these deficiencies. Specifically, extended downregulation protocols, ample use of gonadotropins for ovarian stimulation, and conservative management of endometriomas have all been suggested as means to optimize in-vitro fertilization outcomes for women with endometriosis.
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Review Article Endometriosis and assisted reproductive technologies: are outcomes affected? - Neal G. Mahutte - Aydin Arici Current Opinion in Obstetrics & Gynecology 13(3):p 275-279, June 2001. The preponderance of recent data suggests that endometriosis does not adversely affect in-vitro fertilization pregnancy rates. However, many studies demonstrate impaired oocyte quality, decreased fertilization, and compromised implantation rates. Such findings give insight into the mechanisms by which endometriosis may impact on fertility, and provide clues as how to focus assisted reproductive technologies in order to overcome these deficiencies. Specifically, extended downregulation protocols, ample use of gonadotropins for ovarian stimulation, and conservative management of endometriomas have all been suggested as means to optimize in-vitro fertilization outcomes for women with endometriosis. Copyright © 2001 Lippincott Williams & Wilkins, Inc.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Infertility, Female Outcome Assessment, Health Care Reproductive Techniques Endometriosis Endometriosis Female Gonadotropins Gonadotropins Humans Infertility, Female Infertility, Female Infertility, Female Pregnancy

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (43)

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