Ovarian endometriosis and peritoneal endometriosis: are they different entities from a fertility perspective?

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This review examines peritoneal and ovarian endometriosis, finding that in-vitro fertilization outcomes are not impaired by surgery, particularly if ovarian cortex damage is avoided.

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This paper is a narrative review of literature on the pathogenesis and natural evolution of peritoneal endometriosis, with special attention to fertility-related outcomes, including the role of medical versus surgical management in infertility. It discusses recurrence risk and reports that in-vitro fertilization and embryo transfer results in ovarian endometriosis are not impaired when ovarian cortex damage is avoided, while noting that further studies are needed to determine whether oocytes from endometriosis patients are intrinsically altered and could yield lower-quality embryos. A key limitation is that the work synthesizes heterogeneous prior studies rather than presenting new original data. Relevance to endometriosis: it directly reviews fertility perspectives comparing ovarian endometriosis and peritoneal endometriosis and highlights IVF/embryo-transfer outcomes in ovarian endometriosis.

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Abstract

This review summarizes the recent literature concerning new data on the pathogenesis of peritoneal endometriosis and its natural evolution. Indeed, the main concern in endometriosis is the choice of treatment in cases of infertility problems: medical or surgical. This concern could hypothetically be avoided if endometriosis were considered as a spontaneously regressive phenomenon. The present paper also discusses the risk of recurrence and the results of in-vitro fertilization and embryo transfer in cases of ovarian endometriosis. Whatever type of surgery is performed, the results of in-vitro fertilization and embryo transfer are not impaired, especially if damage to the ovarian cortex is avoided. Further studies are required to determine if oocytes from endometriosis patients are altered and could be responsible for the development of lower quality embryos.
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Article (Scientific journals) Ovarian endometriosis and peritoneal endometriosis: are they different entities from a fertility perspective? 2002 • In Current Opinion in Obstetrics and Gynecology, 14 (3), p. 283-288 Peer Reviewed verified by ORBiNisolle M 2002.pdf Publisher postprint (118.04 kB) All documents in ORBi are protected by a user license. copy to clipboard copied Abstract : [en] This review summarizes the recent literature concerning new data on the pathogenesis of peritoneal endometriosis and its natural evolution. Indeed, the main concern in endometriosis is the choice of treatment in cases of infertility problems: medical or surgical. This concern could hypothetically be avoided if endometriosis were considered as a spontaneously regressive phenomenon. The present paper also discusses the risk of recurrence and the results of in-vitro fertilization and embryo transfer in cases of ovarian endometriosis. Whatever type of surgery is performed, the results of in-vitro fertilization and embryo transfer are not impaired, especially if damage to the ovarian cortex is avoided. Further studies are required to determine if oocytes from endometriosis patients are altered and could be responsible for the development of lower quality embryos. Disciplines : Reproductive medicine (gynecology, andrology, obstetrics) Nisolle, Michelle ; Centre Hospitalier Universitaire de Liège - CHU > Gynécologie-Obstétrique CHR Language : English Title : Ovarian endometriosis and peritoneal endometriosis: are they different entities from a fertility perspective? Publication date : June 2002 Journal title : Current Opinion in Obstetrics and Gynecology ISSN : 1040-872X eISSN : 1473-656X Publisher : Lippincott Williams & Wilkins, Philadelphia, United States - Pennsylvania Volume : 14 Issue : 3 Pages : 283-288 Peer reviewed : Peer Reviewed verified by ORBi Available on ORBi : since 16 November 2011 Scopus citations® 26 Scopus citations® without self-citations without self-citations 26 OpenCitations 24 OpenAlex citations 24 - Von Rokitansky C. (1860) Uterine gland proliferation in uterine and ovarian sarcomas. Zeitschrift Gesellschaft fur Aerzte zu Wien 37:577. - Sampson J.A. (1927) Peritoneal endometriosis due to menstrual dissemination of endometrial tissue into the peritoneal cavity. Am J Obstet Gynecol 14:422-469. - Nisolle M., Donnez J. (1997) Peritoneal endometriosis, ovarian endometriosis, and adenomyotic nodules of the rectovaginal septum are three different entities. Fertil Steril 68:585-596. - Nisolle M., Casanas-Roux F., Marbaix E. 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mesh:D004715endometriosisinfertility

MeSH descriptors

Endometriosis Fertilization in Vitro Ovarian Diseases Peritoneal Diseases Endometriosis Endometriosis Female Humans Ovarian Diseases Ovarian Diseases Peritoneal Diseases Peritoneal Diseases Pregnancy

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