Validation study of nonsurgical diagnosis of endometriosis

Eskenazi B, B Eskenazi, Brenda Eskenazi, Warner M, Marcella Warner, M Warner, Bonsignore L, Luigi Bonsignore, L Bonsignore, David L. Olive, Olive D, D Olive, Samuels S, S Samuels, Steven J. Samuels, P Vercellini, Paolo Vercellini
Fertility and sterility · 2001 · vol. 76(5) , pp. 929–935 · doi:10.1016/s0015-0282(01)02736-4 · PMID:11704113 · W2040488564
article OA: closed CC0 ⤵ 215 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This study aimed to validate non-surgical methods for diagnosing endometriosis, evaluating their accuracy and effectiveness in identifying the condition without invasive procedures.

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Abstract

ObjectiveTo determine whether the surgical diagnosis of endometriosis can be predicted using symptoms, signs, and ultrasound findings.DesignProspective study (study sample); retrospective record review (test sample).SettingHospital of Desio (study sample) and Mangiagalli Hospital (test sample), Italy.Patient(s)Ninety women scheduled to undergo laparoscopy or laparotomy (study sample); 120 women who underwent laparoscopy (test sample).InterventionThe study sample group was interviewed before surgery about infertility and dysmenorrhea, dyspareunia, and noncyclic pelvic pain and each member had a pelvic examination and a transvaginal ultrasound. At surgery, endometriosis was noted. For the test sample, the same information was abstracted from medical records after laparoscopy.Main outcome measure(s)The ability of symptoms, signs, and ultrasound to predict endometriosis at surgery. A classification tree was developed with the study sample and evaluated with the test sample.Result(s)Ovarian endometriosis, but not nonovarian endometriosis, could be reliably predicted with noninvasive tools. Ultrasound and examination best predicted ovarian endometriosis, correctly classifying 100% of cases with no false positive diagnoses in the study sample. Similar results were found in the test sample.Conclusion(s)Noninvasive tools may be used to identify women with ovarian, but not nonovarian endometriosis, with excellent agreement with surgical diagnosis.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Adult Endometriosis Endometriosis Female Humans Middle Aged Ovarian Diseases Ovarian Diseases Physical Examination Prospective Studies Retrospective Studies Ultrasonography

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References (31)

Cited by (50)

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