Current opinion in obstetrics & gynecology

PURPOSE OF REVIEW: Adenomyosis is increasingly diagnosed in reproductive-aged patients, particularly those undergoing assisted reproductive technology, due to advances in imaging and standardized diagnostic criteria. Its association with in…

PURPOSE OF REVIEW: Perimenopause is a clinically distinct stage in which abnormal uterine bleeding, fibroids, adenomyosis, endometriosis, and adnexal pathology may require surgical evaluation. Management is complex because symptom burden an…

PURPOSE OF REVIEW: Extrapelvic endometriosis can be associated with significant morbidity. Diagnosis is often delayed due to atypical and nonspecific symptoms, as well as the rarity of endometriosis implants in most extrapelvic sites. This …

PURPOSE OF REVIEW: Over the last few decades, genomics has become integral to understanding disease pathophysiology, improving diagnostics, and refining treatment strategies. Endometriosis, uterine fibroids, and adenomyosis are highly preva…

PURPOSE OF REVIEW: The purpose of this study is to review the current evidence on the efficacy and safety of transvaginal radiofrequency ablation (TRFA) for the treatment of uterine fibroids and adenomyosis in infertile women, and to assess…

PURPOSE OF REVIEW: Endometriosis was once thought to affect only reproductive-aged women. However, 2-5% of postmenopausal individuals remain affected. Guidance for this group is limited. This review outlines an updated approach to postmenop…

PURPOSE: Recurrent pregnancy loss (RPL) is a multifactorial condition with varying definitions across professional societies and is often misunderstood. This review summarizes recent insights into genetic, paternal, anatomic, metabolic, imm…

PURPOSE OF REVIEW: Progesterone plays a pivotal role in implantation and ongoing pregnancy. In the context of assisted reproductive technology (ART), and in particular frozen embryo transfer (FET), increasing evidence suggests that serum pr…

PURPOSE OF REVIEW: This review synthesizes current evidence on how endometrial polyps, leiomyomas, adenomyosis, and endometriosis influence endometrial receptivity, emphasizing phenotype-specific effects, molecular mechanisms, and implicati…

PURPOSE OF REVIEW: The purpose of this article is to provide a comprehensive review of recent literature addressing diagnoses and conditions that intersect pediatric and adolescent gynecology (PAG) and complex benign gynecology (CBG) to inf…

PURPOSE OF REVIEW: Adenomyosis is characterized by the presence of ectopic endometrial glands and tissue within the myometrium. The diagnosis and detection of adenomyosis on imaging have been hindered by a lack of consensus among clinicians…

PURPOSE OF REVIEW: This review synthesizes current evidence on pathophysiology, diagnosis, and management strategies for endometriosis of the urinary tract, emphasizing the urgent need for multidisciplinary care to prevent long-term complic…

PURPOSE OF REVIEW: Atypical endometriosis is a distinct subtype of endometriosis, characterized by specific histopathologic findings. It is thought to be a precursor lesion to endometriosis-associated ovarian cancers, particularly clear-cel…

PURPOSE OF REVIEW: This review highlights important advances in image-guided therapies for patients with benign complex gynecological conditions, beyond uterine artery embolization for leiomyomata (fibroids). RECENT FINDINGS: A comprehensi…

PURPOSE OF REVIEW: We present a review of the natural progression, response to hormonal therapy, and risk of malignancy associated with deep endometriosis (DE) to guide evidence-based discussion of conservative treatment. RECENT FINDINGS: …

PURPOSE OF REVIEW: Endometriosis is a chronic inflammatory condition that frequently presents with gastrointestinal (GI) symptoms that overlap with disorders such as irritable bowel syndrome, inflammatory bowel disease, and gastroparesis, l…

PURPOSE OF REVIEW: Endometriosis is a chronic inflammatory condition that significantly affects women's quality of life and fertility. Despite advancements in treatment, many areas of uncertainty persist in clinical management. This review …

PURPOSE OF REVIEW: Adenomyosis, characterized by ectopic endometrial tissue within the myometrium, causes chronic pelvic pain, heavy bleeding, and reduced fertility. Nowadays, diagnosis relies heavily on imaging, primarily transvaginal ultr…

PURPOSE OF REVIEW: Hysterectomy remains one of the most performed gynecologic procedures, yet its application in young and nulliparous individuals raises complex ethical, medical, and psychosocial considerations. As early detection of gynec…

PURPOSE OF REVIEW: This article reviews recent advances in ultrasound elastography in diagnosing and evaluating the normal nongravid uterus and the infertile uterus in the gynecologic patient. RECENT FINDINGS: Focusing on the most recent p…

PURPOSE OF REVIEW: Adenomyosis is a common cause of abnormal uterine bleeding (AUB), dysmenorrhea, and pelvic pain. Definitive diagnosis and treatment have historically been by uterine histopathology at time of hysterectomy; however, advanc…

PURPOSE OF REVIEW: Hysterectomy is the most common gynecologic surgical procedure performed on women in the United States. While there are data supporting that hysterectomy for benign indication often does not reduce sexual function and may…

PURPOSE OF REVIEW: The analysis of microbiome in association with female health is today a "hot topic" with the main focus on microbes in the female reproductive tract. Nevertheless, recent studies are providing novel information of the pos…

PURPOSE OF REVIEW: The analysis of microbiome in association with female health is today a "hot topic" with the main focus on microbes in the female reproductive tract. Nevertheless, recent studies are providing novel information of the pos…

PURPOSE OF REVIEW: Endometriosis is a chronic, often debilitating, disease which is typically managed with surgery and hormonal medications. However, many patients feel they lack agency when managing endometriosis symptoms. The purpose of t…