Does ovarian surgery for endometriomas impair the ovarian response to gonadotropin?

Jacques Donnez, J. Donnez, Donnez J, Wyns C, C Wyns, Christine Wyns, M. Nisolle, Nisolle M, Michelle Nisolle
Fertility and sterility · 2001 · vol. 76(4) , pp. 662–665 · doi:10.1016/s0015-0282(01)02011-8 · PMID:11591395 · W2111065868
article OA: bronze CC0 ⤵ 135 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This study investigated whether ovarian surgery for endometriomas negatively affects the ovaries' response to gonadotropin stimulation.

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Abstract

ObjectiveTo evaluate the ovarian response to stimulation conducted for IVF treatment in women who have undergone conservative surgery for endometriomas.DesignRetrospective study with prospective selection of participants and controls.SettingUniversity infertility clinic.Patient(s)A series of 374 women who underwent in vitro fertilization (IVF). The study group consisted of 85 patients with ovarian endometriomas who had undergone laparoscopic surgery in an attempt to become pregnant, but had failed within a year of surgery. The control group consisted of 289 patients with tubal factor infertility.Intervention(s)IVF-embryo transfer procedures.Main outcome measure(s)Stimulation parameters, fertilization, implantation, and pregnancy rates were analyzed in both groups.Result(s)There was no significant difference between the two groups in stimulation parameters or IVF outcome.Conclusion(s)A total of 820 cycles were analyzed. A similar IVF-ET outcome was observed in patients with endometriosis after ablation of endometriomas compared to women with tubal factors. In conclusion, endometrioma surgery by internal wall vaporization does not impair IVF outcome. The clinical pregnancy rate was respectively 37.4% and 34.6% in the endometriosis group and the control group.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Gonadotropins Ovarian Diseases Ovary Ovary Adult Embryo Transfer Endometriosis Endometriosis Fallopian Tube Diseases Fallopian Tube Diseases Female Fertilization in Vitro Gonadotropins Humans Infertility, Female Infertility, Female Laparoscopy Ovarian Diseases Ovarian Diseases

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