Endometrial Pinopode and αvβ3 Integrin Expression Is Not Impaired in Infertile Patients with Endometriosis
Endometrial pinopode formation and αvβ3 integrin expression were not significantly different in infertile women with endometriosis compared to infertile or fertile control groups.
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This study evaluated endometrial receptivity by measuring pinopode formation and αvβ3 integrin expression in infertile women with stage I or II endometriosis compared with two control groups: infertile women with unexplained infertility and fertile women undergoing tubal sterilization. Using natural-cycle timing, each participant underwent two endometrial biopsies at postovulatory day +7 to +8 and again 4 days later within a single menstrual cycle. The authors found no statistically significant differences in αvβ3 integrin expression or pinopode formation between the endometriosis group and either control group. This paper is centrally about endometriosis — it tests whether implantation-marker expression is impaired in infertile stage I–II endometriosis during the window of implantation.
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Cited by (14)
- Endometrial Receptivity in Women with Endometriosis 2024
- GnRH agonist administration prior to embryo transfer in freeze-all cycles of patients with endometriosis or aberrant endometrial integrin expression 2017
- Expression of PGR, HBEGF, ITGAV, ITGB3 and SPP1 genes in eutopic endometrium of infertile women with endometriosis during the implantation window: a pilot study 2017
- Ultrastructural Evaluation of Eutopic Endometrium of Infertile Women With and Without Endometriosis During the Window of Implantation: A Pilot Study 2017
- Endometrial biomarkers for the non-invasive diagnosis of endometriosis 2016
- Molecular Biology of Endometriosis 2016
- Surgery for Benign Gynecological Disorders Improve Endometrium Receptivity: A Systematic Review of the Literature 2016
- Gel-free proteomics reveals neoplastic potential in endometrium of infertile patients with stage IV ovarian endometriosis 2015
- Expression pattern of osteopontin and v 3 integrin during the implantation window in infertile patients with early stages of endometriosis 2012
- Characterization of periostin expression in human endometrium and endometriotic lesions 2012
- Does endometrial integrin expression in endometriosis patients predict enhanced in vitro fertilization cycle outcomes after prolonged GnRH agonist therapy? 2009
- Infertilidad y endometriosis 2007
- Combination of 17β-estradiol with the environmental pollutant TCDD is involved in pathogenesis of endometriosis via up-regulating the chemokine I-309–CCR8 2007
- Leukaemia inhibitory factor and interleukin 11 levels in uterine flushings of infertile patients with endometriosis 2006
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