Juan Balasch

OBJECTIVE: The purpose of the study was to develop an easily applicable predictive model to predict deep infiltrating endometriosis in patients with ovarian endometrioma. STUDY DESIGN: We performed a retrospective analysis of 178 consecuti…

'To whom reprint requests should be sent The luteal phase of 20 infertile women with endometriosis who were treated with danazol (600 mg daily for 6 months) was studied by basal body temperature, plasma progesterone (P), oestradiol (Ej…

IntroductionRecent reports consider endometriosis to be an immunological disorder, thus suggesting potential efficacy of immunomodulators for its treatment. The aim of this study was to assess the effects of oral administration of pentoxify…

STUDY QUESTION: Are the levels of total circulating cell-derived microparticles (cMPs) and circulating tissue factor-containing microparticles (cMP-TF) increased in patients with endometriosis? SUMMARY ANSWER: The levels of total cMP, but n…

STUDY QUESTION: Are the levels of biologically active and the most toxic dioxin-like substances in adipose tissue of patients with deep infiltrating endometriosis (DIE) higher than in a control group without endometriosis? SUMMARY ANSWER: D…

To evaluate the benefit of bowel preparation (BP) before a transvaginal ultrasound (TVUS) to detect and describe nodules of deep infiltrating endometriosis (DIE) affecting the anterior rectal wall. The rectal wall of patients with suspected…

The aim of this study was to describe the adenomyosis ultrasound findings and its relation with different locations of endometriosis in patients with previously known endometriosis. Patients with previously know endometriosis and followed i…

Purpose Several environmental toxicants (ETs), including dioxins and dioxin-like compounds (DLCs), perfluorochemicals, organochlorine pesticides, phthalates, and heavy metals (especially cadmium with its estrogen-like properties in animal m…

BACKGROUND: To study endometrial receptivity in terms of osteopontin (OPN) and αvβ3 integrin expression and co-expression in infertile women with early stages of endometriosis. METHODS: We investigated the immunohistochemical expression and…

Cytokines, and specifically interleukin 6 (IL-6) and interleukin 8 (IL-8), have been associated with the pathogenesis of endometriosis. We studied serum concentrations of IL-6 and IL-8 in patients with deep infiltrating endometriosis (DIE) …

ObjectiveTo investigate the effect of two laparoscopic techniques for treatment of ovarian endometriomas on recurrence rate.DesignProspective randomized clinical trial.SettingUniversity teaching hospital.Patient(s)Ninety women with ovarian …

BACKGROUND: Surgical treatment has modest efficacy for the treatment of infertility associated with early-stage endometriosis. Immunomodulation with pentoxifylline is considered as a new strategy potentially useful in treating endometriosis…

ObjectiveTo assess the effect of surgeon's increasing experience in conservative laparoscopic surgery of women with rectovaginal endometriosis on the surgical outcome of these patients recurrence rate.DesignProspective cohort study.SettingU…

Unexplained infertility is a diagnosis made by exclusion after a complete infertility evaluation. Standard testing for infertility should include semen analysis (evaluated according to the WHO criteria), assessment of ovulation (serum proge…

ObjectiveTubal ligation may reduce the ovarian blood flow and lead to tissue damage to the ovary. If so, this may also result in a significant decrease of the total follicular pool. We performed a long-term evaluation of ovarian reserve and…

PurposeTo investigate endometrial receptivity in terms of pinopode formation and alphavbeta3 integrin expression in infertile women with endometriosis during natural cycles.MethodsWe investigated the expression of alphavbeta3 integrin and p…

La endometriosis es una de las enfermedades más enigmáticas y controvertidas de la ginecología y, por ello, no existe un tratamiento idóneo para la misma, especialmente cuando hay que preservar la fertilidad de la mujer. Las terapéuticas ap…

Immunopathophysiological mechanisms in endometriosis-associated reproductive failure were studied in appropriate populations: infertile and fertile women with and without endometriosis. The incidence of sera positive for any of the autoanti…

The present study is the first prospective randomized controlled trial of the effect of pentoxifylline on future fertility in infertile women with asymptomatic minimal or mild endometriosis. After completion of a basic infertility workup an…

We report a case of pituitary-ovarian suppression obtained with sequential danazol/leuprolide acetate administration in a patient undergoing in vitro fertilization and unresponsive to leuprolide acetate alone and sequential oral contracepti…

PROBLEM: Hyperactivated macrophages are implicated in the pathophysiology of endometriosis-associated infertility. This study investigates transferrin receptor expression (CD71) as a marker of hyperactivity in peritoneal macrophages of infe…