Endometrial receptivity in terms of pinopode expression is not impaired in women with endometriosis in artificially prepared cycles

Juan A. García-Velasco, J A Garcia-Velasco, Garcia-Velasco JA, G Nikas, Nikas G, George Nikas, Remohí J, José Remohı́, J Remohí, António Pellicer, A Pellicer, Pellicer A, Carlos Simón, C Simón
Fertility and sterility · 2001 · vol. 75(6) , pp. 1231–1233 · doi:10.1016/s0015-0282(01)01774-5 · PMID:11384658 · W2171853578
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This study investigated endometrial pinopode expression in women with endometriosis during artificially prepared cycles and found no impairment.

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Abstract

ObjectiveTo assess endometrial receptivity in terms of pinopode expression in women with endometriosis.DesignProspective, observational study.SettingOocyte donation program at the Instituto Valenciano de Infertilidad.Patient(s)Twelve women with endometriosis as the only cause of infertility.Intervention(s)Pinopode expression pattern analysis by scanning electron microscopy in two sequential endometrial biopsies obtained in the same cycle of each patient.Main outcome measure(s)Pinopode pattern and pregnancy rates.Result(s)Pinopode expression in women with endometriosis did not differ from that of patients without endometriosis undergoing artificial cycles. Similarly, the clinical outcome in these women was comparable to that of the general population included in the oocyte donation program. The pregnancy rate per transfer was 46.7%.Conclusion(s)These results show that in women with endometriosis undergoing oocyte donation under hormone replacement therapy, pinopode expression is not altered, suggesting that endometrial receptivity in women with this disease remains unaltered.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometrium Biopsy Cell Membrane Cell Membrane Cell Membrane Embryo Transfer Endometriosis Endometriosis Endometriosis Endometrium Endometrium Female Humans Infertility, Female Infertility, Female Microscopy, Electron, Scanning Oocyte Donation Pregnancy Pregnancy Rate

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Cited by (16)

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