Expression of integrin adhesion molecules in endometrium and endometriosis

J E Bridges, Jackie Bridges, Andrew Prentice, A Prentice, W Roche, W. R. Roche, P Englefield, Eric J. Thomas, E J Thomas
British journal of obstetrics and gynaecology · 1994 · vol. 101(8) , pp. 696–700 · doi:10.1111/j.1471-0528.1994.tb13187.x · PMID:7947505 · W1995909293
article OA: closed CC0 ⤵ 38 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This study compared integrin expression in eutopic and ectopic endometrium from patients with endometriosis, finding differences between endometrial stages but no difference between eutopic and ectopic tissue.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

OBJECTIVE: To compare the expression of cell adhesion molecules by endometrium and endometriosis. DESIGN: A comparative study of integrin expression, determined immunohistochemically, in eutopic and ectopic endometrium biopsied synchronously from patients with endometriosis diagnosed at laparoscopy or laparotomy. SETTING: University Departments of Obstetrics and Gynaecology, and Pathology, Southampton; Department of Obstetrics and Gynaecology, Newcastle upon Tyne. SAMPLES: Eighteen paired samples of endometria and endometriosis. RESULTS: A wide distribution of collagen-laminin receptor proteins was demonstrated. alpha 1 integrin expression was limited to secretory endometrium. beta 3 expression was only demonstrated on proliferative endometrium. CONCLUSIONS: Expressions of the integrin proteins differed between the various elements of the endometrium. Cyclical changes in integrin expression also were demonstrated. No difference in cell adhesion molecule expression was seen when comparing endometrial and endometriosis samples.

My notes (saved in your browser only)

Condition tags

mesh:D004715endometriosis

MeSH descriptors

Cell Adhesion Molecules Endometriosis Endometrium Cell Adhesion Molecules Endometriosis Endometrium Endothelium, Vascular Endothelium, Vascular Female Humans Immunohistochemistry Integrins Integrins Receptors, Collagen Receptors, Laminin Receptors, Laminin

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (24)

Cited by (38)

Source provenance

europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:11:24.284338+00:00
License: CC0 · commercial use OK