Quelles nouveautés sur l’endométriose ?

C Dupas, Cyrielle Dupas, Dupas C, Christin-Maitre S, S Christin-Maitre, Sophie Christin‐Maître
Annales d'endocrinologie · 2008 · vol. 69 , pp. S53–S56 · doi:10.1016/s0003-4266(08)73969-6 · PMID:18954860 · W1968962719
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This paper reviews recent advancements and new findings in the field of endometriosis.

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Abstract

Endometriosis concerns 6 to 10 % of the female population, and is responsible for severe pelvic pain and infertility. This estrogen dependant disease, is characterized by the presence of endometrial tissue outside of the uterus cavity. Although his physiopathology remains poorly understood, recent data have focused on angiogenesis, which could represent a key factor for the growing of lesions of endometriosis. New antiangiogenesis treatments represent a therapeutic hope, and have been tested in vitro or in vivo in mice. Those drugs have proven their efficacy on endometriotic lesions. Secondly, several hypothesis are discussed to explain infertility in endometriosis. In particular, a direct impact of peritoneal fluid from women with endometriosis on sperm DNA could be involved.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Angiogenesis Inhibitors Angiogenesis Inhibitors Animals Disease Models, Animal Endometriosis Endometriosis Endometriosis Endometrium Endometrium Female Humans Incidence Infertility, Female Infertility, Female Mice Neovascularization, Pathologic Neovascularization, Pathologic Pelvic Pain Pelvic Pain

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (21)

Cited by (3)

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License: CC0 · commercial use OK