A Prentice
No ORCID on file
· 30 papers in corpus
meta-analysis
2016
BACKGROUND: Endometrial biopsies are undertaken in premenopausal women with abnormal uterine bleeding but the risk of endometrial cancer or atypical hyperplasia is unclear. OBJECTIVES: To conduct a systematic literature review to establish…
guideline
2014
STUDY QUESTION: What is the optimal management of women with endometriosis based on the best available evidence in the literature? SUMMARY ANSWER: Using the structured methodology of the Manual for ESHRE Guideline Development, 83 recommend…
meta-analysis
2007
BACKGROUND: Endometriosis is defined as the presence of endometrial tissue (stromal and glandular) outside the normal uterine cavity. Conventional medical and surgical treatments for endometriosis aim to remove or decrease the deposits of e…
meta-analysis
2007
BACKGROUND: Endometriosis is a common gynaecological condition which affects many women of reproductive age worldwide and is a major cause of pain and infertility. The modern oral contraceptive pill is widely used to treat pain occurring as…
meta-analysis
2005
BACKGROUND: Endometriosis is a common gynaecological condition that affects women and can lead to painful symptoms and infertility. It affects women's quality of life greatly, impacting on their careers, everyday activities, sexual and non-…
lab-animal
2004
BACKGROUND: Women with endometriosis have elevated levels of cyclooxygenase-2 (COX-2) in peritoneal macrophages and endometriotic tissue. Inhibition of COX-2 has been shown to reduce inflammation, angiogenesis and cellular proliferation. It…
meta-analysis
2003
BACKGROUND: Gonadotrophin-releasing hormone analogues (GnRHas) are generally well tolerated, and are effective in relieving the symptoms of endometriosis (Prentice 2003). Unfortunately the low oestrogen state that they induce is associated …
meta-analysis
2001
BACKGROUND: Endometriosis is defined as the presence of endometrial tissue (stromal and glandular) outside the normal uterine cavity. Conventional medical and surgical treatments for endometriosis aim to remove or decrease deposits of ectop…
meta-analysis
2001
BACKGROUND: Endometriosis is defined as the presence of endometrial tissue (stromal and glandular) outside the normal uterine cavity. Conventional medical and surgical treatments for endometriosis aim to remove or decrease deposits of ectop…
review
2001
Many doctors, both general practitioners and specialists, find endometriosis difficult to manage. Equally, many patients are dissatisfied with the care they receive. Endometriosis is the presence of endometrium at sites outside the endometr…
review
2000
Chronic pelvic pain is a symptom of poorly understood aetiology. Pelvic congestion and psychological factors have been identified as important aetiological factors but surprisingly few studies of therapies directed at these aetiologies have…
other
2000
meta-analysis
2000
BACKGROUND: Endometriosis is a gynaecological condition that presents either with the problem of infertility or with painful symptoms. The clinical observation of an apparent resolution of symptoms during pregnancy gave rise to the concept …
review
1999
meta-analysis
1999
BACKGROUND: Endometriosis is a common gynaecological condition that frequently presents with the symptom of pain. The precise pathogenesis (mode of development) of endometriosis is unclear but it is evident that endometriosis arises by the …
rct
1999
OBJECTIVE: To determine whether an educational package could influence the management of menorrhagia, increase the appropriateness of choice of non-hormonal treatment, and reduce referral rates from primary to secondary care. DESIGN: Rando…
meta-analysis
1999
BACKGROUND: Endometriosis is a common gynaecological condition that frequently presents with the symptom of pain. The precise pathogenesis (mode of development) of endometriosis is unclear but it is evident that endometriosis arises by the …
other
1998
Concerns about high rates of hysterectomy have increased interest in alternative surgical and medical treatments for menorrhagia. Hysteroscopic procedures that ablate and resect the endometrium without hysterectomy have been widely adopted …
observational
1997
Endometriosis is characterized by an increase in the number, activation and secretory activity of peritoneal fluid macrophages. Factors regulating the activation of these cells may be important in the pathophysiology of this disease. In thi…
observational
1997
Endometriosis, a debilitating disease associated with infertility, is characterized by the prolonged presence of ectopic endometrial tissue and the involvement of activated peritoneal fluid macrophages. Apoptosis, which occurs in both endom…
meta-analysis
1997
BACKGROUND: Endometriosis is a major women's health-care problem. It causes pain and/or infertility, and affects millions of women worldwide. Endometriosis is defined according to histological criteria by the presence of tissue resembling e…
lab-animal
1996
Angiogenesis is important in the pathophysiology of endometriosis, a condition characterized by implantation of ectopic endometrium in the peritoneal cavity. Vascular endothelial growth factor (VEGF) is a potent angiogenic factor involved i…
observational
1996
Active endometriosis is characterized by hypervascularization both within and surrounding the implant; therefore the presence of angiogenic factors in the peritoneal environment would be of great importance. Vascular endothelial growth fact…
case-report
1995
(1995). Gynaecological case reports: Successful medical treatment of sub-diaphragmatic endometriosis. Journal of Obstetrics and Gynaecology: Vol. 15, No. 3, pp. 206-206.
other
1994
OBJECTIVE: To compare the expression of cell adhesion molecules by endometrium and endometriosis. DESIGN: A comparative study of integrin expression, determined immunohistochemically, in eutopic and ectopic endometrium biopsied synchronous…