Surgery for Benign Gynecological Disorders Improve Endometrium Receptivity: A Systematic Review of the Literature

Önder Çelik, Onder Celik, Mustafa Acet, Tansu Küçük, Tansu Kucuk, Esra Tuştaş Haberal, Esra Tustas Haberal, Tuba Acet, Murat Bozkurt, Levent Şahi̇n, Levent Sahin, Fatma Ferda Verit, Eray Caliskan, Eray Çalışkan
Reproductive sciences (Thousand Oaks, Calif.) · 2016 · vol. 24(2) , pp. 174–192 · doi:10.1177/1933719116654993 · PMID:27485359 · W2466050556
review OA: closed CC0 ⤵ 7 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This systematic review evaluated existing publications to determine if reproductive surgery for benign gynecological disorders improves endometrial receptivity.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This systematic review evaluated publications on whether reproductive surgery for benign gynecological disorders (including peritoneal endometriosis, ovarian endometrioma, adenomyosis, leiomyomas, endometrial polyps, uterine septum, and hydrosalpinges) improves endometrial receptivity, rather than focusing solely on pregnancy outcomes. The authors summarize proposed mechanisms by which surgery may remove mechanical effects and reduce detrimental signaling from diseased tissues, and note that endometrial receptivity markers are inconsistently assessed across studies. They emphasize that randomized controlled trial evidence and prior systematic reviews/meta-analyses directly answering whether surgery improves receptivity are lacking. This paper is centrally about endometriosis and adenomyosis within a broader systematic review of how surgery for benign gynecological disorders affects endometrial receptivity.

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MeSH descriptors

Embryo Implantation Endometrium Genital Diseases, Female Embryo Implantation Endometrium Female Genital Diseases, Female Humans Pregnancy Pregnancy Rate Treatment Outcome

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