A comparison of oestrogen receptor and progesterone receptor expression in endometrial polyps and endometrium of premenopausal women

Xiang Peng, Tin Chiu Li, E Xia, Chengcai Xia, Liu Y, Y. Liu, Dihua Yu
In: Journal of Obstetrics and Gynaecology · 2009 · vol. 29(4) , pp. 340–346 · doi:10.1080/01443610902878775 · PMID:19835506 · W2165293475
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This study found higher estrogen receptor and lower progesterone receptor expression in endometrial polyps compared to adjacent endometrial tissue in premenopausal women.

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Abstract

SUMMARY: Polyps from the endometrium is a common cause of abnormal uterine bleeding and sometimes cause infertility and pelvic pain. The objective of this study was to measure the expression of hormone receptors (oestrogen receptor and progesterone receptor) in endometrial polyps and compare the results to surrounding endometrial tissue. This prospective study recruited 53 women prior to menopause. The study showed that the expression of oestrogen receptor was higher whereas the expression of progesterone receptor was lower than that of adjacent endometrial tissue. The results suggest that abnormal expression of hormone receptor contribute to endometrial polyps formation.

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