Ovarian hyperstimulation syndrome (OHSS) is a severe complication of controlled ovarian hyperstimulation (COH) during in vitro fertilization (IVF) treatment, characterized by increased capillary permeability.Vascular endothelial growth fact…
(Abstracted from Eur J Obstet Gynecol Reprod Biol 2024:302:104–110 Endometrial thickening without vaginal bleeding is frequently considered an indication for referral for pathological evaluation, though gynecologists debate whether this is …
< 0.05) higher than that of the contralateral luminal endometrium (157%, IQR 114-176%). There was no significant difference in Mucin1 expression in the glandular epithelium. There was no significant difference in Glycodelin expression in lu…
Endometriosis is a chronic disorder characterized by the presence of endometrial glands and stroma outside the uterine cavity. It affects 8%-10% of women in their reproductive years, and represents a major clinical problem with deleterious …
Myostatin (MSTN) is member of the transforming growth factor β (TGF-β) superfamily and was originally identified in the musculoskeletal system as a negative regulator of skeletal muscle growth. The functional roles of MSTN outside of the mu…
Research questionIs there a difference in the ovarian reserve 1 year post-operatively in those who used a haemostatic sealant or bipolar diathermy for haemostasis during laparoscopic ovarian cystectomy for ovarian endometriomas?DesignThis w…
Chronic pelvic pain (CPP) is a common gynaecological complaint with a similar consultation rate to low back pain, asthma, or migraine. It is estimated that up to 15–20% of women aged 18–50 years have experienced CPP for more than 1 year. Ne…
(Abstracted from Fertil Steril 2019;112:707–717) Chronic endometriosis (CE), a state of chronic inflammation in the endometrial lining, has been associated with reproductive failure and is diagnosed based on the presence of CD138+ plasma ce…
BackgroundThis clinical trial aimed to compare the clinical efficacy of highly purified human menopausal gonadotropin (HP-HMG) plus recombinant human follicle-stimulating hormone (rFSH) versus rFSH alone on controlled ovarian stimulation (C…
This study means to investigate a combination of noninvasive methods in diagnosis of minimal or mild endometriosis expecting to narrow down the range of laparoscopic exploration for female infertility.It is a retrospective case control stud…
BACKGROUND AND OBJECTIVE: Endometrial angiogenesis is a prerequisite for successful pregnancy. Optical coherence tomography (OCT) is a non-invasive physically optical imaging technique widely used in ophthalmology and cardiology. However, t…
OBJECTIVE: To evaluate the effect of haemostatic sealant compared with bipolar coagulation on ovarian reserve after laparoscopic cystectomy for ovarian endometriomas. DESIGN: Patient-blinded, randomised controlled trial. SETTING: University…
BACKGROUND: The reproductive impact of adenomyosis and endometriosis is widely researched but the extent of these impacts remains elusive. It has been demonstrated that endometriosis, in particular, is known to result in subfertility but en…
BackgroundIt is postulated that women suffered from recurrent implantation failure (RIF) have different endometrial receptivity compared to those who experienced with idiopathic recurrent miscarriage (RM). In this study, expression of commo…
Objective: To evaluate the effects of estradiol on endometrial regeneration and stromal fibrosis after endometrial curettage. Study Design: This is an experimental, prospective study. Combining ovariectomized rabbits and different doses of …
The management of adenomyosis remains a great challenge to practicing gynaecologists. Until recently, hysterectomy has been the only definitive treatment in women who have completed child bearing. A number of nonsurgical and minimally invas…
OBJECTIVE: To compare the expression of G-protein-coupled estrogen receptor (GPER) in the junctional zone and outer myometrium of the proliferative and secretory phases of women with and without adenomyosis. METHODS: = 18). Protein and tota…
PROBLEM: The relationship between hepatitis B (HBV) infection in infertile couples seeking in vitro fertilization (IVF) treatment and infertility causes is unknown. METHODS OF STUDY: A total of 831 infertile couples attending our unit seeki…
BackgroundThe pregnancy outcome of the unicornuate uterus is associated with an increased risk of miscarriage, cervical incompetence, and a number of obstetric complications. However, at present, there is no accepted treatment method for wo…
Transvaginal laparoscopy (TVL) was introduced in 1998 (Gordts et al. Hum Reprod 1998;13:99–103) but its uptake has been slow. Globally, very few centres offer it as an alternative to traditional laparoscopy. There are reasons for this. Firs…