PurposeThe purpose of this study is to report two cases of monozygotic quadruplet and triplet pregnancies following single embryo transfer (ET).MethodsA 29-year-old woman and a 34-year-old woman underwent ART treatment in two affiliated Uni…
What is the recommended diagnostic work-up of female genital anomalies according to the European Society of Human Reproduction and Embryology (ESHRE)/European Society for Gynaecological Endoscopy (ESGE) system? The ESHRE/ESGE consensus for …
Objective. Women with infertility and recurrent miscarriages may have an overlapping etiology. The aim of this study was to compare the pregnancy loss in pregnancies after IVF treatment with spontaneous pregnancies in women with recurrent m…
ObjectiveTo investigate the relationship between endometrial expressions of angiogenic factors around the time of embryo implantation and P level before oocyte retrieval during IVF-ET treatment.DesignRetrospective study.SettingUniversity As…
OBJECTIVE: To compare the expression of oxytocin receptor in the uterine junctional zone of the fundus and isthmus in the proliferative and secretory phases in women with and without adenomyosis. DESIGN: Experimental prospective clinical st…
BACKGROUND: Endometriosis is a disease known to be detrimental to fertility. Women with endometriosis, and the presence of endometrioma, may require artificial reproductive techniques (ART) to achieve a pregnancy. The specific impact of end…
BACKGROUND: Overweight and obese women have been shown to have an increased risk of recurrent miscarriage as well as other adverse reproductive outcomes, but it is yet unclear whether this is due to an effect on the endometrium, embryo or b…
BACKGROUND: Pelvic adhesions are found in up to 50% of women with CPP during investigative surgeries and adhesiolysis is often performed as part of their management although the causal or casual association of adhesions, and the clinical be…
OBJECTIVE: This prospective study was designed to determine whether the expression of cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF) in the endometrial tissue obtained from the peri-implantation period of women with …
The endometrial-myometrial interface (EMI) is a specific functional region of uterus. However, our knowledge on EMI ultrastructure both in normal uterus and adenomyosis is far from enough to understand its pathology. In this study, used the…
OBJECTIVE: To compare the effect of transcervical resection of the endometrium (TCRE) combined with levonorgestrel-containing intrauterine system (LNG-IUS) versus LNG-IUS alone in the treatment of adenomyosis. STUDY DESIGN: A total of 43 pa…
AIM: In this article, we hypothesized that significant pain in the immediate postoperative period is due to a deeper degree of thermal ablation, down to the myometrial layer, and consequently an increased likelihood of successful outcome. M…
ObjectiveTo investigate the expression of integrin β3 and osteopontin (OPN) in the eutopic endometrium of adenomyosis and to characterize possible endometrial defects in adenomyosis.Study designTwenty-eight adenomyosis patients and 27 contr…
OBJECTIVE: To evaluate the feasibility and value of abdominal ultrasound guided access for transvaginal hydrolaparoscopy (THL). STUDY DESIGN: One hundred and ninety-three infertile women were retrospectively included. A total of 31 subject…
Endometriosis has become an increasingly common health condition of women worldwide. It is not only the main cause of severe pelvic pain, but also one of the most common causes of infertility, which has a significant impact on women's quali…
ObjectiveTo evaluate the value of transvaginal hydrolaparoscopy (THL) in infertile women with abnormal hysterosalpingogram results but with no history of previous pelvic surgery and with normal gynecological examination and vaginal sonograp…
SUMMARY: Polyps from the endometrium is a common cause of abnormal uterine bleeding and sometimes cause infertility and pelvic pain. The objective of this study was to measure the expression of hormone receptors (oestrogen receptor and prog…
This study aimed to examine the rate of re-operation in women with endometriosis over a 10-year period. This was a retrospective study set in a university hospital in the UK. Notes of all women diagnosed with endometriosis were reviewed and…
This study prospectively evaluated the impact of transcervical resection of endometrium (TCRE) on uterine and ovarian haemodynamics. The study group comprised 35 women with abnormal (excessive) uterine bleeding who underwent TCRE. The patie…
Despite improvement in the success of IVF, reproductive surgery will remain an important option and complement to assisted reproductive technologies (ART) for many couples. Reproductive surgery should be considered as the first-line treatme…
BACKGROUND: Pelvic adhesions are a significant cause of morbidity and are associated with infertility and pain. The three pro-inflammatory cytokines interleukin (IL)-1, IL-6 and tumour necrosis factor (TNF)-alpha are involved in adhesion fo…
The levonorgestrel intrauterine system (LNG-IUS or Mirena®) is an efficient contraceptive device which also brings about a profound reduction in menstrual blood loss. It is therefore a recognised treatment for menorrhagia. A common cause of…
There was a significant increase in the number of laparoscopic procedures performed in the Reproductive and Surgery Unit at the Jessop Hospital for Women over the 7 year period from 1991 to 1997. The three most common procedures were adhesi…