Does non-cavity distorting intramural fibroid affect endometrium around the time of embryo implantation?

Haiyan Yang, Xiaoyan Chen, Yingyu Liu, Jing Luo, Rui Huang, Yiwei Zhao, Tin Chiu Li, Xiaowu Huang
In: Human Fertility · 2023 · vol. 26(4) , pp. 712–719 · doi:10.1080/14647273.2023.2264498 · PMID:37815345 · W4387473253
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study investigated intramural fibroids and found altered Mucin1 expression in luminal epithelium, but no differences in other endometrial markers, leaving the impact on implantation uncertain.

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Abstract

< 0.05) higher than that of the contralateral luminal endometrium (157%, IQR 114-176%). There was no significant difference in Mucin1 expression in the glandular epithelium. There was no significant difference in Glycodelin expression in luminal and glandular epithelium, uNK cells density or histological dating results between the paired endometrial samples. In conclusion, it is uncertain whether the altered expression of Mucin1 in luminal epithelium alone may have impact on implantation when other markers are not changed.

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last seen: 2026-06-10T17:14:06.276822+00:00
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