In Vitro Fertilization for Endometriosis-Associated Infertility

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AI-generated summary by claude@2026-06, 2026-06-09

This article discusses the impact of endometriosis and endometriomas on IVF outcomes, examines the role of surgery, reviews IVF protocols, and assesses the effect of ovarian stimulation on endometriosis progression.

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Abstract

Endometriosis is an enigmatic disease affecting 10-15% of reproductive aged women and is encountered in 25-35% of women suffering from infertility. IVF is an effective tool to overcome endometriosis-associated infertility when expectant management or surgery fails. Direct IVF should be envisioned if the female age is greater than 38 year and infertility is long lasting. Likewise, semen characteristics or tubal status that is incompatible with natural conception mandates going straight to IVF. IVF, not only bypasses the distortion of pelvic anatomy associated with advanced stage endometriosis, but also removes gametes from a hostile peritoneal environment. In this article, we address the impact, if any, of endometriosis and endometriomason IVF outcome, whether surgical treatment of early-stage disease, endometriomas or deep infiltrating endometriosis would enhance pregnancy rates in IVF, which protocol to employ for controlled ovarian hyperstimulation for IVF and finally the impact, if any, of controlled ovarian hyperstimulation for IVF on progression of endometriosis.

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Condition tags

mesh:D004715endometriosisdie_deep_infiltratinginfertility

MeSH descriptors

Embryo Transfer Endometriosis Fertilization in Vitro Infertility, Female Ovulation Induction Adult Embryo Transfer Endometriosis Endometriosis Endometrium Endometrium Female Fertilization in Vitro Gynecologic Surgical Procedures Gynecologic Surgical Procedures Humans Infertility, Female Infertility, Female Infertility, Female Ovarian Reserve

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References (60)

Cited by (7)

Source provenance

europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:17:39.907309+00:00
License: CC0 · commercial use OK