Prise en charge en FIV en cas d’endométriose, RPC Endométriose CNGOF-HAS

Chauffour C, C Chauffour, J-L Pouly, Jean Luc Pouly, A-S Gremeau, Gremeau AS, A.-S. Grémeau
Gynecologie, obstetrique, fertilite & senologie · 2018 · vol. 46(3) , pp. 338–348 · doi:10.1016/j.gofs.2018.02.015 · PMID:29523480 · W2793653040
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⚙ AI-generated summary by claude@2026-07, 2026-07-08 ⓘ

Endometriosis presence does not alter IVF pregnancy rates, but prolonged ovulation suppression may improve chances, and surgery is only recommended after IVF failure or for recurrence management.

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Abstract

Should the presence of endometriosis change the management of assisted reproductive technology? There is no difference in pregnancy rate after IVF between an agonist or antagonist protocol in patients with endometriosis, so the choice between one or the other of these protocols is free. But the review of the literature has shown an improvement in the chances of pregnancy in case of prolonged ovulation suppression before stimulation for IVF with a GnRH agonist analogue or with oral contraception, especially in cases of severe endometriosis. Endometriosis, regardless of the stage and type of lesions, would have no effect on the IVF results in terms of pregnancy rate and live birth rate, but with a lower number of oocytes collected, especially in cases of severe endometriosis. In a context of superficial endometriosis without pain and of infertility, surgical treatment of superficial endometriosis is not recommended just to increase the chances of pregnancy in IVF. Surgery may have a place in case of failure of IVF to improve the results of the ART. In case of recurrence of endometriosis, surgery is not better than IVF, a medico-surgical concertation is recommended. In addition, studies on ovulation stimulation for IVF do not show any aggravation of the symptoms associated with endometriosis lesions, or an acceleration of its progression, or an increase in the rate of recurrence of the disease.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Infertility, Female Reproductive Techniques, Assisted Endometriosis Endometriosis Female Fertility Agents, Female Fertility Agents, Female Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Humans Infertility, Female Infertility, Female

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (69)

Cited by (4)

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