The outcome of in vitro fertilization in advanced endometriosis with previous surgery: A case-controlled study

Aboulghar MA, Mohamed Aboulghar, Mohamed A Aboulghar, Mansour RT, Ragaa Mansour, Ragaa T Mansour, Gamal I. Serour, Serour GI, Hesham Al-Inany, Hesham G Al-Inany, Al-Inany HG, Mona M. Aboulghar, Aboulghar MM
American journal of obstetrics and gynecology · 2003 · vol. 188(2) , pp. 371–375 · doi:10.1067/mob.2003.13 · PMID:12592242 · W2015288281
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This case-controlled study investigated the success rates of in vitro fertilization in women with advanced endometriosis who had undergone prior surgical treatment.

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Abstract

ObjectiveThis study was undertaken to evaluate the outcome of in vitro fertilization (IVF) in patients with advanced pelvic endometriosis and previous surgical treatment.Study designA case controlled study was performed.ResultsPatients with the diagnosis of stage IV endometriosis with previous surgical treatment were treated by IVF (group A = 85). An age-matched group of patients (group B = 177) with tubal factor infertility were treated with the same protocol of IVF. In group A, cycle cancellation because of poor response occurred in 29.7% compared with 1.1% in the control group (relative risk 26.03, 95% CI 6.02-112.45). There were 13 (15.3%) clinical pregnancies per stimulated cycle in group A compared with 93 (52.5%) clinical pregnancies in the control group, P <.0001 (odds ratio 0.29, 95% CI 0.15-0.55).ConclusionThe outcome of IVF in stage IV endometriosis with previous surgery was significantly lower compared with an age-matched group of tubal factor infertility.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Fertilization in Vitro Infertility, Female Adult Case-Control Studies Embryo Transfer Endometriosis Fallopian Tube Diseases Fallopian Tube Diseases Female Humans Infertility, Female Pregnancy Pregnancy Rate Treatment Outcome

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