Morphokinetics in Embryos from Patients with Endometriosis

Paolo Giovanni Artini, Elena Pisacreta, Susanna Cappellini, Elena Carletti
In: ISGE Series · 2020 · pp. 123–131 · doi:10.1007/978-3-030-57866-4_12 · W3110782489
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-14 ⓘ

This paper investigates endometriosis, a condition where endometrial tissue grows outside the uterus and is influenced by estrogenic stimuli.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text ⓘ

This chapter discusses endometriosis as an estrogen-influenced heterotopy characterized by cyclical proliferation and breakdown of ectopic endometrial tissue, focusing on how it relates to women’s reproductive health. It provides background context for the field, citing that endometriosis is common and associated with contested aspects of diagnosis and management, and it references prior evidence linking endometriosis to oocyte and embryo-related outcomes. The main limitation is that the provided text is an overview section without study-specific methods, results, or quantified morphokinetic findings. Relevance to endometriosis: the paper/chapter is explicitly about endometriosis and frames embryo and reproductive implications within that condition, even though the excerpt itself does not report new embryo morphokinetic data.

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Abstract

Endometriosis is one of the most common and controversial women-related diseases. It is defined as the presence and cyclical growth of functional endometrial tissue (glands and stroma) outside the uterus, commonly occurring on the ovaries and peritoneum [1]. Endometriosis could be considered as a heterotopy in which the ectopic endometrium is influenced by estrogenic stimuli and cyclically proliferates, and becomes a secretory tissue and breaks down, as well as the endometrial mucosa [2]. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

References

Giudice LC, Kao LC. Endometriosis. Lancet. 2004;364(9447):1789–99. Pescetto G, Cecco LD, Pecorari D, Ragni N. Ginecologia e ostetricia, vol. 1. Roma: SEU; 2017. p. 15–32. Xu B, et al. Oocyte quality is decreased in women with minimal or mild endometriosis. Sci Rep. 2015;5:10779. The Practice Committee of the American Society for Reproductive Medicine. Endometriosis and infertility: a committee opinion. Fertil Steril. 2012;98(3):591–8. Augoulea A, et al. Pathogenesis of endometriosis: the role of genetics, inflammation and oxidative stress. Arch Gynecol Obstet. 2012;286(1):99–103. Singh N, et al. Effect of endometriosis on implantation rates when compared to tubal factor in fresh non donor in vitro fertilization cycles. J Hum Reprod Sci. 2014;7(2):143–7. Hadfield R, et al. Delay in the diagnosis of endometriosis: a survey of women from the USA and the UK. Hum Reprod. 1996;11(4):878–80. Eskenazi B, Warner ML. Epidemiology of endometriosis. Obstet Gynecol Clin N Am. 1997;24(2):235–58. Kavoussi SK, et al. New paradigms in the diagnosis and management of endometriosis. Curr Opin Obstet Gynecol. 2016;28(4):267–76. Da Broi MG, et al. Increased concentration of 8-hydroxy-2′-deoxyguanosine in follicular fluid of infertile women with endometriosis. Cell Tissue Res. 2016;366(1):231–42. Malvezzi H, et al. Peritoneal fluid of women with endometriosis reduces SOD1 in bovine oocytes in vitro maturation. Cell Tissue Res. 2018;372(3):621–8. Jianini B, et al. Peritoneal fluid from infertile women with minimal/mild endometriosis compromises the meiotic spindle of metaphase II bovine oocytes: a pilot study. Reprod Sci. 2017;24(9):1304–11. Stilley JA, Birt JA, Sharpe-Timms KL. Cellular and molecular basis for endometriosis-associated infertility. Cell Tissue Res. 2012;349(3):849–62. Brosens I. Endometriosis and the outcome of in vitro fertilization. Fertil Steril. 2004;81(5):1198–200. Olivennes F. Results of IVF in women with endometriosis. J Gynecol Obstet Biol Reprod (Paris). 2003;32(8 Pt 2):S45–7. Veeck LL. An atlas of human gametes and conceptuses: an illustrated reference for assisted reproductive technology. London: Taylor & Francis; 1999. Sathananthan AH, Gunasheela S. Human oocyte and embryo assessment for ART. In: Human preimplantation embryo selection. Boca Raton, FL: CRC Press; 2007. p. 1–14. Rienzi LF, Ubaldi F. Oocyte retrieval and selection. In: Texbook of assisted reproductive technologies. Laboratory and clinical perspective. Boca Raton, FL: CRC Press; 2009. p. 85–101. Balaban B. The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting. Hum Reprod. 2011;26(6):1270–83. Author information Authors and Affiliations Corresponding author Editor information Editors and Affiliations Rights and permissions Copyright information © 2021 International Society of Gynecological Endocrinology About this chapter Cite this chapter Artini, P.G., Pisacreta, E., Cappellini, S., Carletti, E. (2021). Morphokinetics in Embryos from Patients with Endometriosis. In: Genazzani, A.R., Nisolle, M., Petraglia, F., Taylor, R.N. (eds) Endometriosis Pathogenesis, Clinical Impact and Management. ISGE Series. Springer, Cham. https://doi.org/10.1007/978-3-030-57866-4_12 Download citation DOI: https://doi.org/10.1007/978-3-030-57866-4_12 Published: Publisher Name: Springer, Cham Print ISBN: 978-3-030-57865-7 Online ISBN: 978-3-030-57866-4 eBook Packages: MedicineMedicine (R0)

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endometriosis

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