Luteinized unruptured follicle in the early stages of endometriosis as a cause of unexplained infertility

Y Mio, Yasuyuki Mio, Mio Y, T Toda, Toda T, Harada T, Tasuku Harada, T Harada, Terakawa N, N Terakawa, Naoki Terakawa
American Journal of Obstetrics and Gynecology · 1992 · vol. 167(1) , pp. 271–273 · doi:10.1016/s0002-9378(11)91673-1 · PMID:1442941 · W2040238312
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This study investigates luteinized unruptured follicles as a potential cause of unexplained infertility in women with early-stage endometriosis.

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Abstract

ObjectiveWe attempted to clarify the relationship between luteinized unruptured follicle, which occurs in the early stages of endometriosis, and unexplained infertility.Study designSeventy patients who had unexplained infertility were reviewed.ResultsLaparoscopic examination showed that 47 patients (67%) had endometriosis; of these, 40 (85%) had minimal or mild disease. The incidence of luteinized unruptured follicle was higher (p < 0.05) in patients who had endometriosis (35%/patient and 25%/cycle) compared with patients who did not have endometriosis (11%/patient and 7%/cycle). Degenerated oocyte cumuli were collected in 6 (43%) of 14 luteinized unruptured follicles diagnosed by transvaginal ultrasound.ConclusionsThese results show that luteinized unruptured follicle is common in patients who have mild or minimal endometriosis and that it may be one of the causes of endometriosis-associated infertility. Transvaginal ultrasound-guided follicular puncture of luteinized unruptured follicle during the mid luteal phase may be useful in establishing a definitive diagnosis of luteinized unruptured follicle.

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Condition tags

endometriosisinfertility

MeSH descriptors

Corpus Luteum Endometriosis Endometriosis Infertility, Female Ovarian Follicle Corpus Luteum Endometriosis Endometriosis Female Humans Infertility, Female Oocytes Oocytes Ovarian Follicle Ovarian Follicle Ultrasonography

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (35)

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