New aspects of the pathophysiology of endometriosis and associated infertility.
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This paper proposes that pelvic endometriosis and associated infertility may be a consequence of infertility caused by unruptured luteinized follicles, citing higher peritoneal fluid hormone levels in ovulatory cycles.
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Abstract
After ovulation, peritoneal fluid contains concentrations of progesterone and of 17 beta-estradiol that are 5 to 20 times higher than plasma concentrations in women with ovulatory cycles but not in women with unruptured luteinized follicles. Since viable endometrial cells were found in the peritoneal fluid of over 50% of women, both with and without endometriosis, a new hypothesis is presented about the etiology of pelvic endometriosis and the association of pelvic endometriosis and infertility: pelvic endometriosis could be the consequence of infertility caused by the unruptured luteinized follicle.
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Cited by (50)
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- Is retrograde menstruation a universal, recurrent, physiological phenomenon? A systematic review of the evidence in humans and non-human primates 2024
- New Understanding of Diagnosis, Treatment and Prevention of Endometriosis 2022
- Review on endometriosis surgery 2021
- Peritoneal fluid progesterone and progesterone resistance in superficial endometriosis lesions 2021
- Pathogenesis Based Diagnosis and Treatment of Endometriosis 2021
- The Genetic-Epigenetic Pathophysiology of Endometriosis: A Surgeon’s View 2020
- Cystic ovarian endometriosis and infertility: arguments for an early but less aggressive surgical treatment 2020
- The epidemiology of endometriosis is poorly known as the pathophysiology and diagnosis are unclear 2020
- Epithelial–Mesenchymal Transition in Endometriosis—When Does It Happen? 2020
- Pathogenesis of endometriosis: the genetic/epigenetic theory 2018
- Epidemiological and Clinical Risk Factors for Endometriosis 2017
- Molecular and Cellular Pathogenesis of Endometriosis 2017
- Epidemiology of subtle, typical, cystic, and deep endometriosis: a systematic review 2016
- The Presence of Endometrial Cells in Peritoneal Fluid of Women With and Without Endometriosis 2016
- Analytical Hypotheses on Possible Etiology and Types of Endometriosis 2015
- Pain related genes in endometriosis: A meta-analysis 2015
- Die Wirkung von hCG auf die Dezidualisierung ektoper endometrialer Läsionen als therapeutischer Ansatz zur Behandlung der Endometriose 2014
- The role of the peritoneum in the pathogenesis of endometriosis 2013
- Biology of Eutopic and Ectopic Endometrium in Women with Endometriosis 2011
- Co-expression of bone morphogenetic protein 6 with estrogen receptor a in endometriosis 2011
- Semi-invasive Diagnosis of Endometriosis Doctoral Thesis 2010
- An endometriosis classification, designed to be validated 2010
- Post-Translational Modifications and Protein-Specific Isoforms in Endometriosis Revealed by 2D DIGE 2010
- Quantity and quality of retrograde menstruation: a case control study 2009
- Polymorphic (CAG)n repeats in the androgen receptor gene 2009
- Estrogen receptor-alpha gene (T/C) Pvu II polymorphism in endometriosis and uterine fibroids. 2009
- Baboon Model for Endometriosis 2009
- Pathophysiology of Cyclic Hemorrhagic Ascites and Endometriosis 2008
- Therapeutic efficacy of hysterosalpingography with special reference to application of hydrostatic pressure during the procedure. 2007
- Passagem de células endometriais para a cavidade peritoneal durante histeroscopia diagnóstica 2007
- [Endometriosis in delayed scarring of postpartum eutocic episiorrhaphy. Integral aspects and a case report]. 2005
- Laser surgery for endometriosis 2005
- The pathogenesis of endometriosis: the endometrium - mesothelium dialogue 2004
- Animal Models for Research on Endometriosis 2003
- Endometriosis is a Surgical Disease 2003
- The epidemiology of endometriosis 2003
- The Epidemiology of Endometriosis 2002
- A defective expression of ICAM-1 (CD54) on secretory endometrial cells is associated with endometriosis 2002
- Endometriosis, retrograde menstruation and peritoneal inflammation in women and in baboons 2002
- Apoptosis in endometrial glandular and stromal cells in women with and without endometriosis 2001
- Endometriosis: Radiologic-Pathologic Correlation 2001
- Umbilical endometriosis after unprotected removal of uterine pieces through the umbilicus 2000
- Endometriosis 2000
- Pathogenesis of Endometriosis: The Role of Peritoneal Fluid 1999
- Could tight garments cause endometriosis? 1999
- Implantation versus Infiltration: The Sampson versus the Endometriotic Disease Theory 1999
- Adhesion of shed menstrual tissue in an in-vitro model using amnion and peritoneum: a light and electron microscopic study 1999
- Biases in the endometriosis literature 1998
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- last seen: 2026-08-25T06:10:03.373225+00:00
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