Impact of ovarian endometrioma on oocytes and pregnancy outcome in in vitro fertilization

Takahiro Suzuki, Suzuki T, Shun-ichiro Izumi, Shun‐ichiro Izumi, Matsubayashi H, Hidehiko Matsubayashi, Awaji H, H. Awaji, Hideo Awaji, Kikuo Yoshikata, Yoshikata K, Makino T, Tsunehisa Makino
Fertility and sterility · 2005 · vol. 83(4) , pp. 908–913 · doi:10.1016/j.fertnstert.2004.11.028 · PMID:15820799 · W2026790109
article OA: bronze CC0 ⤵ 116 in-corpus citations
🔓 Open OA copy View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This study investigated how ovarian endometriomas affect oocyte quality and pregnancy rates in women undergoing in vitro fertilization.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

ObjectiveTo evaluate the effect of endometriosis and the presence of an ovarian endometrioma on outcomes of conventional in vitro fertilization (IVF).DesignRetrospective study.SettingReproductive Unit, Department of Obstetrics and Gynecology, Tokai University Hospital.Patient(s)Group A: 80 cycles with ovarian endometriomas; group B: 248 cycles with endometriosis but without endometrial cysts at the time of oocyte retrieval; group C: 283 cycles undergoing IVF because of tubal factor without endometriosis.Intervention(s)All conventional in vitro fertilization-embryo transfer (IVF-ET) with previous diagnostic laparoscopy. An endometrioma was diagnosed by direct aspiration at the time of oocyte retrieval.Main outcome measure(s)Retrieved number of oocytes, fertilization rate, embryo quality, implantation rate, pregnancy rate, and live birth rate for all cases. In group A, the number of retrieved oocytes in relation to the volume of the endometrioma and affected laterality.Result(s)Fewer oocytes were retrieved from groups A and B than from group C (P<.005). The number of retrieved oocytes was not dependent on the volume of endometrial cyst(s). Fertilization rates were similar among the groups. Group A had slightly but not significantly higher rates of morphologically good-quality embryos (group A: 67.2%, group B: 63.0%, group C: 58.1%), implantation (group A: 14.1%, group B: 11.7%, group C: 11.3%), and pregnancy (group A: 25.3%, group B: 22.3%, group C: 23.9%).Conclusion(s)Endometriosis affects oocyte number but not embryo quality or pregnancy outcome, irrespective of the presence of an ovarian endometrioma.

My notes (saved in your browser only)

Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Fertilization in Vitro Infertility, Female Infertility, Female Oocytes Adult Endometriosis Endometriosis Female Humans Infertility, Female Laparoscopy Oocytes Ovulation Induction Pregnancy Pregnancy Outcome Retrospective Studies

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (34)

Cited by (50)

Source provenance

europepmc
last seen: 2026-07-27T06:15:28.040536+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:15:41.664291+00:00
License: CC0 · commercial use OK