Treatment of endometrioma for improving fertility

Umberto Leone Roberti Maggiore, Gupta JK, Janesh Gupta, Janesh Kumar Gupta, Simone Ferrero
European journal of obstetrics, gynecology, and reproductive biology · 2016 · vol. 209 , pp. 81–85 · doi:10.1016/j.ejogrb.2016.02.035 · PMID:26968428 · W2343578925
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This systematic review analyzes the effectiveness of endometrioma treatments for improving fertility outcomes in affected women.

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Abstract

Endometrioma is a frequent clinical manifestation of endometriosis. It is controversial how endometriomas may affect women's fertility. This review addresses: the impact of the endometrioma per se and of its surgical treatment on ovarian physiology, on the ovarian reserve, on spontaneous conception and pregnancy outcomes, and on IVF/ICSI outcomes. Based on current evidence, although there are plausible biological detrimental effects on the ovarian cortex surrounding the endometrioma and an impairment of the normal ovarian physiology, the clinical impact of the endometrioma per se is not significantly altered. There is a negligible detrimental effect on ovarian reserve with spontaneous ovulation not being impaired. Conversely, surgical excision of an endometrioma reduces ovarian reserve as measured by AMH levels. Studies investigating the impact of the endometrioma per se and of its surgical treatment in women requiring IVF/ICSI show similar implantation rates, clinical pregnancy rates and live birth rates between women with endometrioma and controls.

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Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Infertility, Female Endometriosis Endometriosis Female Fertility Humans Infertility, Female Infertility, Female Ovarian Reserve Pregnancy Pregnancy Outcome Pregnancy Rate Treatment Outcome

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (73)

Cited by (47)

Source provenance

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License: CC0 · commercial use OK