The impact on ovarian reserve after laparoscopic ovarian cystectomy versus three-stage management in patients with endometriomas: a prospective randomized study

Dimitrios Tsolakidis, Pados G, George Pados, Vavilis D, Dimitrios Vavilis, Dimitrios Athanatos, Athanatos D, Tsalikis T, Tryfon Tsalikis, Anastasia Giannakou, Giannakou A, Tarlatzis BC, Basil C Tarlatzis
Fertility and sterility · 2009 · vol. 94(1) , pp. 71–77 · doi:10.1016/j.fertnstert.2009.01.138 · PMID:19393996 · W2087935689
article OA: closed CC0 ⤵ 169 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This prospective randomized study compared the impact on ovarian reserve between laparoscopic ovarian cystectomy and three-stage management for patients with endometriomas.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

ObjectiveTo investigate the effect of two different laparoscopic methods on ovarian reserve in patients with ovarian endometriomas.DesignProspective, randomized clinical trial.SettingEndoscopy unit of a university hospital.Patient(s)Twenty women with endometriomas.Intervention(s)Patients were randomly selected to undergo either laparoscopic cystectomy for endometrioma (group 1) or the "three-step procedure" (group 2). Before and 6 months after laparoscopy all patients were evaluated, and 12 months postoperatively they underwent ultrasound scan examination.Main outcome measure(s)The primary end point was ovarian reserve damage based on the alterations of anti-Müllerian hormone (AMH). Secondary end points were the changes of antral follicle count and serum concentration of FSH, LH, E(2), and inhibin B.Result(s)Mean serum AMH was reduced significantly from 3.9-2.9 ng/mL in group 1 compared with the reduction from 4.5-3.99 ng/mL in group 2.Conclusion(s)Ovarian reserve determined by AMH is less diminished after the three-step procedure compared with cystectomy of endometriomas.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Laparoscopy Oocytes Ovary Ovary Adult Disease Management Endometriosis Female Humans Laparoscopy Oocytes Oocytes Ovary Ovary Pilot Projects Prospective Studies Treatment Outcome Ultrasonography

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (52)

Cited by (50)

Source provenance

europepmc
last seen: 2026-07-26T06:08:39.051465+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:14:11.755070+00:00
License: CC0 · commercial use OK