The impact on ovarian reserve after laparoscopic ovarian cystectomy versus three-stage management in patients with endometriomas: a prospective randomized study

Dimitrios Tsolakidis, Pados G, George Pados, Vavilis D, Dimitrios Vavilis, Dimitrios Athanatos, Athanatos D, Tsalikis T, Tryfon Tsalikis, Anastasia Giannakou, Giannakou A, Tarlatzis BC, Basil C. Tarlatzis
Fertility and sterility · 2009 · vol. 94(1) , pp. 71–77 · doi:10.1016/j.fertnstert.2009.01.138 · PMID:19393996 · W2087935689
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This prospective randomized study compared the impact on ovarian reserve between laparoscopic ovarian cystectomy and three-stage management for patients with endometriomas.

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Abstract

OBJECTIVE: To investigate the effect of two different laparoscopic methods on ovarian reserve in patients with ovarian endometriomas. DESIGN: Prospective, randomized clinical trial. SETTING: Endoscopy unit of a university hospital. PATIENT(S): Twenty women with endometriomas. INTERVENTION(S): Patients were randomly selected to undergo either laparoscopic cystectomy for endometrioma (group 1) or the "three-step procedure" (group 2). Before and 6 months after laparoscopy all patients were evaluated, and 12 months postoperatively they underwent ultrasound scan examination. MAIN OUTCOME MEASURE(S): The primary end point was ovarian reserve damage based on the alterations of anti-Müllerian hormone (AMH). Secondary end points were the changes of antral follicle count and serum concentration of FSH, LH, E(2), and inhibin B. RESULT(S): Mean serum AMH was reduced significantly from 3.9-2.9 ng/mL in group 1 compared with the reduction from 4.5-3.99 ng/mL in group 2. CONCLUSION(S): Ovarian reserve determined by AMH is less diminished after the three-step procedure compared with cystectomy of endometriomas.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Laparoscopy Oocytes Ovary Ovary Adult Adult Disease Management Disease Management Endometriosis Endometriosis Female Female Humans Humans Laparoscopy Laparoscopy Oocytes Oocytes

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

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