The Impact of Oxidized Regenerated Cellulose Application during Cystectomy and Drainage in Endometrioma Patients: A Retrospective Cohort Study

Luky S Marwali, Luky Satria Marwali, Marcel Ezra Setiawan, Malvin Emeraldi, Agus Surur Asadi, Aditya Rangga Putera, Rany Ayu Puspitasari
Gynecology and minimally invasive therapy · 2024 · vol. 14(1) , pp. 51–56 · doi:10.4103/gmit.gmit_161_23 · PMID:40143973 · PMC11936393 · W4405888894
article OA: gold CC0
📄 Open PDF View on OpenAlex View on PubMed View at publisher

Abstract

Abstract Objectives: This study aims to determine the impact of oxidized regenerated cellulose (ORC) during cystectomy and drainage on recurrence and ovarian reserve. Materials and Methods: Women aged 18–45 years with endometrioma (pathologically confirmed) who underwent conservative laparoscopy surgery (cystectomy and drainage) using ORC at Fatmawati General Hospital Jakarta, Indonesia, were included in this study. All surgeries were done by complete excision of all endometriosis lesions (especially for excision of deep infiltrating endometriosis and adenomyosis resection). All patients were followed up for 1 year, and the recurrence rate and postoperative anti-Mullerian Hormone (AMH) were evaluated. Results: Twenty patients were included in the cystectomy group and 19 in the drainage group. The researchers found the result was not significant ( P = 0.622) in recurrence rate. AMH was decreased from 3.0 ± 1.8 to 2.1 ± 1.5 in cystectomy with ORC group. Conversely, AMH decreased from 1.4 ± 1.25 to 1.1 ± 0.9 in the drainage with ORC group. The reduction of AMH level was more significant in the cystectomy group ( P = 0.002) than in the drainage group ( P = 0.124). Conclusion: Cystectomy with ORC significantly reduces ovarian reserve. Drainage followed by insertion of ORC to the cyst cavity can be an option to maintain ovarian reserve with a risk of recurrence that is not significantly different from cystectomy.

My notes (saved in your browser only)

Condition tags

endometriosisadenomyosisdie_deep_infiltratingendometrioma

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (46)

Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pmc
last seen: 2026-05-13T20:22:03.195721+00:00
pubmed
last seen: 2026-05-25T00:31:40.731709+00:00
License: CC0 · commercial use OK