Impact of ovarian endometrioma on assisted reproduction outcomes

Sajal Gupta, Gupta S, Agarwal A, Ashok Agarwal, Rishi Agarwal, Agarwal R, J Ricardo Loret de Mola, Loret de Mola JR
Reproductive biomedicine online · 2006 · vol. 13(3) , pp. 349–360 · doi:10.1016/s1472-6483(10)61439-3 · PMID:16984764 · W2118246221
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study investigated the relationship between ovarian endometriomas and outcomes of assisted reproduction, reporting on their impact.

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Abstract

The effects of ovarian endometrioma on fertility outcomes with IVF and embryo transfer have been causally related to poor outcomes. The objective of this meta-analysis was to evaluate the ovarian reserve and ovarian responsiveness to ovarian stimulation and assisted reproduction outcomes in patients with ovarian endometrioma. The odds for clinical pregnancy were not affected significantly in patients with ovarian endometrioma compared with controls, with an overall odds ratio of 1.07 from three studies [95% CI: (0.63, 1.81), P = 0.79]. The overall pregnancy rate was similar with an estimated odds ratio of 1.17 [95% CI: (0.85, 1.60), P = 0.34]. Decreased ovarian responsiveness to ovarian stimulation in patients with ovarian endometrioma may be due to a reduced number of follicles in these patients compared with controls (P = 0.002). Prospective randomized controlled trials are needed to assess whether surgical treatment versus no surgical treatment improves pregnancy outcomes in patients with ovarian endometrioma undergoing assisted reproduction cycles.

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Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Infertility, Female Ovarian Diseases Reproductive Techniques, Assisted Endometriosis Endometriosis Endometriosis Endometriosis Female Fertilization in Vitro Humans Infertility, Female Oocyte Donation Ovarian Diseases Ovarian Diseases Ovarian Diseases Ovarian Diseases Ovarian Follicle Ovarian Follicle Pregnancy

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (77)

Cited by (50)

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