The influence of endometriosis on the success of gamete intrafallopian transfer (GIFT)

M Y Chang, Ming‐Yang Chang, C.-C. Chiang, C H Chiang, T’sang‐T’ang Hsieh, T T Hsieh, Y K Soong, Yung‐Kuei Soong, Kuang‐Hung Hsu, K H Hsu
Journal of assisted reproduction and genetics · 1997 · vol. 14(2) , pp. 76–82 · doi:10.1007/bf02765774 · PMID:9048236 · PMC3454826 · W2334258799
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

Endometriosis patients showed decreased ovarian response to stimulation and fewer oocytes retrieved, but maintained comparable GIFT pregnancy success rates to controls.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

The study evaluated outcomes of gamete intrafallopian transfer (GIFT) in 108 GIFT cycles performed for an endometriosis indication, compared with 156 GIFT cycles performed for other disease indications, using controlled ovarian hyperstimulation with up to seven oocytes transferred and prepared sperm. Although women with endometriosis showed progressively reduced ovarian response and fewer retrieved oocytes with increasing endometriosis severity, clinical pregnancy rates (40.4%, 36.7%, 41.7%), multiple pregnancy rates (34.9%, 27.3%, 45.0%), and early pregnancy loss rates (27.0%, 18.2%, 30.0%) did not differ significantly across endometriosis severity categories or versus nonendometriosis after multivariable adjustment for age, tubal health, active endometriosis/endometriomas, oocyte number, and sperm quality. The authors note that because the number of oocytes needed for GIFT is limited, comparable pregnancy results were observed despite reduced ovarian response. This paper is centrally about endometriosis — it analyzes how endometriosis influences ovarian response and pregnancy outcomes after GIFT.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Gamete Intrafallopian Transfer Gamete Intrafallopian Transfer Analysis of Variance Anthropometry Case-Control Studies Endometriosis Female Humans Logistic Models Multivariate Analysis Pregnancy Pregnancy Outcome Pregnancy Rate Retrospective Studies

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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