Fecundity of infertile women with minimal or mild endometriosis

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This study found that operative laparoscopy in infertile women with minimal or mild endometriosis resulted in higher cumulative pregnancy and survival rates compared to medical treatment or expectant management.

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This study examined fecundity in 151 infertile women with laparoscopy-proved minimal or mild (stage 1–2) endometriosis, comparing operative laparoscopy (n=49), medical treatment (n=59), and expectant management (n=43) over 24 months. Cumulative pregnancy rates differed by management strategy, reported as 36.7%, 30.5%, and 20.9%, and survival analysis showed probabilities of carrying pregnancy beyond 20 weeks of 30.6%, 25.4%, and 16.2%, respectively. The authors concluded that diagnosis and treatment of early endometriosis is beneficial and that laparoscopic surgery appeared to increase fecundity, while noting minimal risk as part of the rationale. This paper is centrally about endometriosis — it specifically evaluates fecundity and pregnancy outcomes in infertile women with minimal or mild endometriosis under different treatment approaches.

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Abstract

Despite significant developments in medical and surgical approaches for treating endometriosis, the optimal therapy has yet to be established. The relationship between prevalence of fecundity and stage of endometriosis according to their management was studied. Of 151 consecutive women with laparoscopy-proved endometriosis stage-1 and 2, operative laparoscopy was performed in 49, medical treatment in 59 and expectant management in 43 cases. During a 24-month period the cumulative pregnancy rates were found to be 36.7%, 30.5% and 20.9% respectively. Survival analysis showed that the probability of carrying the pregnancy beyond 20 weeks were 30.6%, 25.4% and 16.2% respectively. Diagnosis and treatment of early endometriosis is beneficial for the infertile women. Laparoscopic surgery seems to be the milestone of treatment in these cases, increasing the fecundity and involving minimal risk.
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Abstract Despite significant developments in medical and surgical approaches for treating endometriosis, the optimal therapy has yet to be established. The relationship between prevalence of fecundity and stage of endometriosis according to their management was studied. Of 151 consecutive women with laparoscopy-proved endometriosis stage-1 and 2, operative laparoscopy was performed in 49, medical treatment in 59 and expectant management in 43 cases. During a 24-month period the cumulative pregnancy rates were found to be 36.7%, 30.5% and 20.9% respectively. Survival analysis showed that the probability of carrying the pregnancy beyond 20 weeks were 30.6%, 25.4% and 16.2% respectively. Diagnosis and treatment of early endometriosis is beneficial for the infertile women. Laparoscopic surgery seems to be the milestone of treatment in these cases, increasing the fecundity and involving minimal risk. Similar content being viewed by others Author information Authors and Affiliations Additional information Received: 10 September 2001 / Accepted: 25 September 2001 Correspondence to A. Elsheikh Rights and permissions About this article Cite this article Milingos, S., Mavrommatis, C., Elsheikh, A. et al. Fecundity of infertile women with minimal or mild endometriosis . Arch Gynecol Obstet 267, 37–40 (2002). https://doi.org/10.1007/s00404-001-0262-7 Issue date: DOI: https://doi.org/10.1007/s00404-001-0262-7

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Infertility, Female Pregnancy Rate Adult Endometriosis Endometriosis Endometriosis Female Greece Greece Humans Infertility, Female Infertility, Female Pregnancy Prevalence Severity of Illness Index

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