Metabolomics analysis of follicular fluid in women with ovarian endometriosis undergoing in vitro fertilization
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This metabolomics study analyzed follicular fluid from women with ovarian endometriosis undergoing IVF, identifying distinct metabolite profiles associated with the condition.
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Abstract
: estradiol; ESHRE: European Society of Human Reproduction and Embryology; ERETIC: electronic to access in vivo concentration; FF: follicular fluid; FSH: follicle-stimulating hormone; hCG: human chorionic gonadotropin; HEPES: 2-hydroxyethyl-1-piperazineethanesulfonic acid; ICSI: intracytoplasmic sperm injection; IVF: in vitro fertilization; NMR: nuclear magnetic resonance spectroscopy; PCA: principal component analysis; PCOS: polycystic ovary syndrome; PLS-DA: partial least squares discriminant analysis; ppm: parts per million; PULCON: pulse length-based concentration determination; TSP: 3-(trimethylsilyl)-1-propanesulfonic acid sodium salt; VIP: variable importance in projection.
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Cited by (25)
- Precision Therapeutic and Preventive Molecular Strategies for Endometriosis-Associated Infertility 2025
- Ethyl Pyruvate as a Potential Therapeutic Agent for Endometriosis: A Perspective 2025
- Molecular pathogenesis of ovarian endometrioma: mechanistic insights and therapeutic implications† 2025
- The inconsistent pathogenesis of endometriosis and adenomyosis: insights from endometrial metabolome and microbiome 2025
- Metabolite changes in patients with endometriosis: new potential diagnostic and therapeutic targets 2025
- S1PR4 Promotes Cell Viability, Invasion, and Glycolysis via the Mammalian Target of Rapamycin Signaling Pathway in Endometriosis 2025
- Ovarian Endometrioma Disrupts Oocyte-Cumulus Communication and Mitochondrial Function, With Melatonin Mitigating the Effects 2025
- A comprehensive multiplatform metabolomic analysis reveals alterations of 2-hydroxybutyric acid among women with deep endometriosis related to the pesticide trans-nonachlor 2024
- Histone lactylation promotes cell proliferation, migration and invasion through targeting HMGB1 in endometriosis 2023
- Metabolomics analysis of follicular fluid in ovarian endometriosis women receiving progestin-primed ovary stimulation protocol for in vitro fertilization 2023
- Metabolic signature of follicular fluid in infertility-related diseases: a narrative review 2023
- Current Role of Modern Chromatography with Mass Spectrometry and Nuclear Magnetic Resonance Spectroscopy in the Investigation of Biomarkers of Endometriosis 2023
- Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis 2022
- Volatilomics as an Emerging Strategy to Determine Potential Biomarkers of Female Infertility: A Pilot Study 2022
- Elevated prohibitin 1 expression mitigates glucose metabolism defects in granulosa cells of infertile patients with endometriosis 2022
- Discovery and validation of peritoneal endometriosis biomarkers in peritoneal fluid and serum 2021
- Metabolomics in endometriosis: challenges and perspectives for future studies 2021
- Symptomatology and Serum Nuclear Magnetic Resonance Metabolomics; Do They Predict Endometriosis in Fertile Women Undergoing Laparoscopic Sterilisation? A Prospective Cross-sectional Study 2021
- Elevated Levels of Monocyte Chemotactic Protein-1 in the Follicular Fluid Reveals Different Populations among Women with Severe Endometriosis 2020
- A pilot study of discovery and validation of peritoneal endometriosis biomarkers in peritoneal fluid and serum 2020
- Endometriosis Lowers the Cumulative Live Birth Rates in IVF by Decreasing the Number of Embryos but Not Their Quality 2020
- Current biomarkers for the detection of endometriosis 2020
- Transferrin Insufficiency and Iron Overload in Follicular Fluid Contribute to Oocyte Dysmaturity in Infertile Women With Advanced Endometriosis 2020
- Oocyte quality in women with infertility associated endometriosis 2019
- New biomarkers in endometriosis 2019
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- europepmc
- last seen: 2026-08-26T06:08:41.316361+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:19:49.066213+00:00
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