Endometriosis and infertility: a review.
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This review of endometriosis and infertility literature indicates surgical treatment improves fecundity, while IVF is effective in affected patients, with varying management strategies based on disease severity.
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Abstract
The objective of this article is to review the current understanding of the relationship between endometriosis and infertility and the recommended management based on the latest evidence. The article is based on a MEDLINE search and bibliography review of the relevant literature from 1960 to 2003. The exact nature of the relationship between endometriosis and infertility remains uncertain. Surgical treatment of moderate and severe endometriosis improves the monthly fecundity rate. Surgical ablation of minimal and mild endometriosis seems superior to expectant management. Infertile patients with minimal and mild endometriosis can benefit from using clomiphene citrate and intrauterine insemination (IUI) or gonadotropins and IUI. Ovarian suppression should not be used in asymptomatic patients wishing to become pregnant except in the setting of in vitro fertilization and embryo transfer (IVF/ET). Prolonged suppression with gonadotropic-releasing hormone analogues should be considered for endometriosis patients about to undergo an IVF/ET cycle. IVF seems to be effective in endometriosis patients.
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Cited by (43)
- Efeito da administração uterina de CXCL12 (SDF-1), sobre genes reguladores da expressão dos receptores de progesterona sobre o endométrio de camundongos fêmeas com endometriose induzida 2023
- Ovulation induction with clomiphene citrate or letrozole following laparoscopy in infertile women with minimal to mild endometriosis: a prospective randomised controlled trial 2021
- Microarray analysis of cumulus cells in women with ovarian endometriosis undergoing intracytoplasmic sperm injection 2020
- Discerning Endometriosis as a Multifaceted Entity: A Comprehensive Review 2020
- Identification of cells without colony-forming ability in Eutopic endometrial progenitor cells in infertile women with endometriosis in comparison with healthy fertile women in Indian perspective 2019
- The expression of angiotensin II receptors mRNA in granulosa-lutein cells in endometriosis patients who underwent ovarian surgery before in vitro fertilization 2019
- Atherosclerosis in patients with endometriosis 2019
- Metabolomics analysis of follicular fluid in women with ovarian endometriosis undergoing <i>in vitro</i> fertilization 2018
- Клинико-лабораторная эффективность стандартов оказания медицинской помощи при внутреннем эндометриозе 2018
- Transcription regulatory factor expression in T-helper cell differentiation pathway in eutopic endometrial tissue samples of women with endometriosis associated with infertility 2018
- The Hormonal-Immune Abnormalities of Uterus Endometriosis in Women with Thyroid Gland Pathology And Infertility 2018
- Comparing the Frequency of Endometritis in Unexplained Infertility and Anovulatory Infertility 2017
- Detrimental effects of endometriosis on oocyte morphology in intracytoplasmic sperm injection cycles: a retrospective cohort study 2017
- Uterine Cavity Abnormalities in Patients with Endometriosis in Alexandria: A Diagnostic Test Accuracy Study 2017
- The Clinical Usefulness of Endometrial Biopsy for the Diagnosis of Endometriosis in the Work up of Women with Infertility 2016
- Prevalence and Symptomatic Burden of Diagnosed Endometriosis in the United States: National Estimates from a Cross-Sectional Survey of 59,411 Women 2016
- Frequency of Polymorphism Alu Insertion in Progesterone Receptor Gene in Endometriosis 2016
- A R are case of Bilateral Lower Ureteral Endometriosis 2015
- Is Endometriosis a Surgical Disease? 2014
- Ultrasonographic evaluation of anal endometriosis: report of four cases 2014
- [Relationship among anthropometric and gluco-metabolic parameters, bone mineral density and endometriosis]. 2014
- Elevated Peritoneal Fluid TNF-α Incites Ovarian Early Growth Response Factor 1 Expression and Downstream Protease Mediators: A Correlation With Ovulatory Dysfunction in Endometriosis 2013
- Overcoming endometriosis-associated preimplantation embryo developmental anomalies by culture 2013
- Developmental exposure of fetal ovaries and fetal germ cells to endometriosis in an endometriosis model causes differential gene expression in the preimplantation embryos of the first-generation and second-generation embryos 2013
- Cellular and molecular basis for endometriosis-associated infertility 2012
- INFERTILITY, ASSOCIATED WITH ENDOMETRIOSIS, THERAPY: IMMUNOGENOTYPIC PARALELLS 2012
- IMMUNE-GENETICS МARKERS OF GENITAL ENDOMETRIOSIS 2012
- Pathological Aspects of Endometriosis 2012
- Relationship Between Toll‐like Receptor‐4 and <scp>mPGES</scp>‐1 Gene Expression in Local Lesions of Endometriosis Patients 2012
- HMGA gene rearrangement is a recurrent somatic alteration in polypoid endometriosis 2012
- Antioxidant supplementation reduces endometriosis-related pelvic pain in humans 2012
- Endometriosis‐Associated Infertility: Double Intrauterine Insemination Improves Fecundity in Patients Positive for Antiendometrial Antibodies 2011
- Endometriosis e infertilidad 2010
- <i>HMGA1</i> and <i>HMGA2</i> rearrangements in mass‐forming endometriosis 2010
- Endometriosis and<i>in vitro</i>fertilisation: A review 2009
- SIGNIFICANCE OF OXIDATIVE STRESS IN HUMAN REPRODUCTION 2009
- Endometriosis 2009
- The patient with endometriosis: achieving pregnancy 2008
- Caesarean section and tubal infertility: is there an association? 2008
- Reduced Fecundity in Female Rats with Surgically Induced Endometriosis and in Their Daughters: A Potential Role for Tissue Inhibitors of Metalloproteinase 11 2008
- Country of birth and hospitalization for pelvic inflammatory disease, ectopic pregnancy, endometriosis, and infertility: a nationwide study of 2 million women in Sweden 2007
- Laparoscopic Helica Thermal Coagulation for the Treatment of Early Endometriosis 2007
- Tratamento da endometriose 2006
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