Research Priorities for Endometriosis: Recommendations From a Global Consortium of Investigators in Endometriosis
A global consortium of endometriosis investigators updated and created new research recommendations, focusing on pathogenesis, symptoms, diagnosis, management, and policy, with emphasis on infertility and translational research.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
This paper reports a 3rd International Consensus Workshop on Research Priorities in Endometriosis, held in São Paulo in May 2014, with 60 participants from 19 countries. It summarizes consensus recommendations across five areas—pathogenesis/pathophysiology, symptoms, diagnosis/classification/prognosis, disease/symptom management, and research policy—building on prior workshops and updating the status of recommendations from 2011. Forty-one 2011 recommendations remained unchanged, 13 were updated, 2 were completed, and 53 new recommendations were added in 2014, yielding 66 new research priorities overall, with new topics including infertility, patient stratification, emerging-nation research, and greater translational focus; no specific limitations are stated in the provided text. This paper is centrally about endometriosis — it provides a global consensus statement of research priorities for investigating the condition.
Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works
Full text
2,414 characters
· extracted from
oa-html
· 2 sections
· click to expand
Abstract
Keywords
Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.
My notes (saved in your browser only)
Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works
Condition tags
MeSH descriptors
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (100)
- 17β-Hydroxysteroid Dehydrogenase-2 Deficiency and Progesterone Resistance in Endometriosis via openalex
- Aberrant expression of deoxyribonucleic acid methyltransferases DNMT1, DNMT3A, and DNMT3B in women with endometriosis via openalex
- Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis via openalex
- Accuracy of rectal endoscopic ultrasonography and magnetic resonance imaging in the diagnosis of rectal involvement for patients presenting with deeply infiltrating endometriosis via openalex
- Acupuncture for pain in endometriosis via openalex
- A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese via openalex
- Altered Gene Expression Profiling in Endometrium: Evidence for Progesterone Resistance via openalex
- An Italian association study and meta-analysis with previous GWAS confirm <i>WNT4</i>, <i>CDKN2BAS</i> and <i>FN1</i> as the first identified susceptibility loci for endometriosis via openalex
- A nonsynonymous variant of IL1A is associated with endometriosis in Japanese population via openalex
- A Novel Mouse Model of Endometriosis Mimics Human Phenotype and Reveals Insights into the Inflammatory Contribution of Shed Endometrium via openalex
- Anti-angiogenic effects of green tea catechin on an experimental endometriosis mouse model via openalex
- A potential novel treatment strategy: inhibition of angiogenesis and inflammation by resveratrol for regression of endometriosis in an experimental rat model via openalex
- Application of the histone deacetylase inhibitors for the treatment of endometriosis: histone modifications as pathogenesis and novel therapeutic target via openalex
- A Prospective Cohort Study of Vitamins B, C, E, and Multivitamin Intake and Endometriosis via openalex
- Association between endometriosis and the interleukin 1A (IL1A) locus via openalex
- A systematic review of the accuracy of ultrasound in the diagnosis of endometriosis via openalex
- A systematic review on endometriosis during pregnancy: diagnosis, misdiagnosis, complications and outcomes via openalex
- Body size and endometriosis: results from 20 years of follow-up within the Nurses' Health Study II prospective cohort via openalex
- Can anyone screen for deep infiltrating endometriosis with transvaginal ultrasound? via openalex
- Catastrophizing: a predictor of persistent pain among women with endometriosis at 1 year via openalex
- Central changes associated with chronic pelvic pain and endometriosis via openalex
- Central sensitization in urogynecological chronic pelvic pain: a systematic literature review. via openalex
- Childhood and Adolescent Exposures and the Risk of Endometriosis via openalex
- Chinese herbal medicine for endometriosis via openalex
- Chronic pelvic pain and endometriosis: translational evidence of the relationship and implications via openalex
- Clinical outcome after CO2 laser laparoscopic radical excision of endometriosis with colorectal wall invasion combined with laparoscopic segmental bowel resection and reanastomosis via openalex
- Clinical outcome after laparoscopic radical excision of endometriosis and laparoscopic segmental bowel resection via openalex
- Clinical Outcome After Radical Excision of Moderate—Severe Endometriosis With or Without Bowel Resection and Reanastomosis via openalex
- Coffee and caffeine intake and risk of endometriosis: a meta-analysis via openalex
- Correlation Between Altered Central Pain Processing and Concentration of Peritoneal Fluid Inflammatory Cytokines in Endometriosis Patients With Chronic Pelvic Pain via openalex
- Creating Solutions in Endometriosis: Global Collaboration through the World Endometriosis Research Foundation via openalex
- Creating Solutions in Endometriosis: Global Collaboration through the World Endometriosis Research Foundation: via openalex
- Dairy-Food, Calcium, Magnesium, and Vitamin D Intake and Endometriosis: A Prospective Cohort Study via openalex
- Deep endometriosis infiltrating the recto-sigmoid: critical factors to consider before management via openalex
- Deep infiltrating endometriosis is associated with markedly lower body mass index: a 476 case-control study via openalex
- Defining Future Directions for Endometriosis Research: Workshop Report From the 2011 World Congress of Endometriosis in Montpellier, France via openalex
- Diagnostic accuracy of transvaginal ultrasound for non‐invasive diagnosis of bowel endometriosis: systematic review and meta‐analysis via openalex
- Diagnostic value of serum activin A and follistatin levels in women with peritoneal, ovarian and deep infiltrating endometriosis via openalex
- Diet and endometriosis risk: A literature review via openalex
- Dietary fish oil supplementation inhibits formation of endometriosis-associated adhesions in a chimeric mouse model via openalex
- Diffusion tensor imaging and tractography to evaluate sacral nerve root abnormalities in endometriosis-related pain: A pilot study via openalex
- Diminished Ovarian Reserve and Endometriosis: Insult upon Injury via openalex
- Ectopic endometrium-derived leptin produces estrogen-dependent chronic pain in a rat model of endometriosis via openalex
- Ectopic uterine tissue as a chronic pain generator via openalex
- Effect of endometriosis on in vitro fertilization via openalex
- Effect of endometriosis on IVF/ICSI outcome: stage III/IV endometriosis worsens cumulative pregnancy and live-born rates via openalex
- Effect of Two Laparoscopic Techniques for Treatment of Ovarian Endometrioma on Ovarian Reserve via openalex
- Effect of vitamin <scp>C</scp> on the growth of experimentally induced endometriotic cysts via openalex
- Effects of Endometriomas on Ooccyte Quality, Embryo Quality, and Pregnancy Rates in In Vitro Fertilization Cycles: A Prospective, Case-Controlled Study via openalex
- Elevated Peritoneal Expression and Estrogen Regulation of Nociceptive Ion Channels in Endometriosis via openalex
- Endometriosis via openalex
- Endometriosis via openalex
- Endometriosis and Subfertility: Is the Relationship Resolved? via openalex
- Endometriosis and the Enigmatic Question of Progression via openalex
- Endometriosis, assisted reproduction technology, and risk of adverse pregnancy outcome via openalex
- Endometriosis, dysmenorrhoea and diet via openalex
- Endometriosis fertility index: the new, validated endometriosis staging system via openalex
- Endometriosis in adolescents is a hidden, progressive and severe disease that deserves attention, not just compassion via openalex
- Endometriosis in an Adolescent Population: The Emory Experience via openalex
- Enhanced epithelial to mesenchymal transition (EMT) and upregulated MYC in ectopic lesions contribute independently to endometriosis via openalex
- Estrogen Receptor (ER) Agonists Differentially Regulate Neuroangiogenesis in Peritoneal Endometriosis via the Repellent Factor SLIT3 via openalex
- Eutopic Endometrium in Women with Endometriosis: Ground Zero for the Study of Implantation Defects via openalex
- Evaluation of a panel of 28 biomarkers for the non-invasive diagnosis of endometriosis via openalex
- Evidence from a Mouse Model That Epithelial Cell Migration and Mesenchymal-Epithelial Transition Contribute to Rapid Restoration of Uterine Tissue Integrity during Menstruation via openalex
- Exploring the mechanism(s) of endometriosis-related infertility: an analysis of embryo development and implantation in assisted reproduction via openalex
- Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets via openalex
- Genistein causes regression of endometriotic implants in the rat model via openalex
- Genome-wide association meta-analysis identifies new endometriosis risk loci via openalex
- Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis via openalex
- Genome-Wide Association Study Link Novel Loci to Endometriosis via openalex
- Genome-Wide DNA Methylation Analysis Predicts an Epigenetic Switch for GATA Factor Expression in Endometriosis via openalex
- Gluten-free diet: a new strategy for management of painful endometriosis related symptoms? via openalex
- High prevalence of endometriosis in infertile women with normal ovulation and normospermic partners via openalex
- How does endometriosis affect infertility? via openalex
- Imbalance between sympathetic and sensory innervation in peritoneal endometriosis via openalex
- Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries via openalex
- Impact of ovarian endometrioma on oocytes and pregnancy outcome in in vitro fertilization via openalex
- Impact of surgical excision of lesions on pain in a rat model of endometriosis via openalex
- Increased Mast Cell Density in Peritoneal Endometriosis Compared with Eutopic Endometrium with Endometriosis via openalex
- Inhibition of Proliferation of Endometrial Stromal Cells by Trichostatin A, RU486, CDB-2914, N-Acetylcysteine, and ICI 182780 via openalex
- Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity via openalex
- In utero exposures and endometriosis: the Endometriosis, Natural History, Disease, Outcome (ENDO) Study via openalex
- Laparoscopic surgery for endometriosis via openalex
- Mast cells in endometriosis: guilty or innocent bystanders? via openalex
- Molecular Classification of Endometriosis and Disease Stage Using High-Dimensional Genomic Data via openalex
- Molecular Evidence for Differences in Endometrium in Severe Versus Mild Endometriosis via openalex
- Molecular Mechanisms of Treatment Resistance in Endometriosis: The Role of Progesterone–Hox Gene Interactions via openalex
- Molecular Network Analysis of Endometriosis Reveals a Role for c-Jun–Regulated Macrophage Activation via openalex
- Neonatal Menstruation Explains Epidemiological Links between Fetomaternal Conditions and Adolescent Endometriosis via openalex
- Nutrient intake, anthropometric data and correlations with the systemic antioxidant capacity of women with pelvic endometriosis via openalex
- Organochlorine Pesticides and Risk of Endometriosis: Findings from a Population-Based Case–Control Study via openalex
- Outcome of patients with endometriosis in assisted reproduction: results from in-vitro fertilization and oocyte donation via openalex
- Pain scoring in endometriosis: entry criteria and outcome measures for clinical trials. Report from the Art and Science of Endometriosis meeting via openalex
- Pathogenesis and pathophysiology of endometriosis via openalex
- Pathogenic mechanisms in endometriosis-associated infertility via openalex
- Peripheral biomarkers of endometriosis: a systematic review via openalex
- Peripheral changes in endometriosis-associated pain via openalex
- Potential role of endometrial stem/progenitor cells in the pathogenesis of early-onset endometriosis via openalex
- Prevalence of Endometriosis in Adolescent Girls With Chronic Pelvic Pain Not Responding to Conventional Therapy via openalex
- Promoter Hypermethylation of Progesterone Receptor Isoform B (PR-B) in Endometriosis via openalex
Cited by (50)
- Electroacupuncture alleviates endometriosis by suppressing ferroptosis in murine ectopic and eutopic endometria via the Nrf2 pathway 2026
- Nuclear imaging for endometriosis: a promising advance 2026
- Assessment of endometriosis angiogenesis using 99mTc-maraciclatide imaging (DETECT): a single-centre, exploratory, open-label, non-randomised, phase 2 study 2026
- Variation in endometriosis aetiology, potential impact on lesion heterogeneity and the consequences for research and treatment 2026
- Transcriptome profiling to identify blood biomarkers for peritoneal endometriosis 2025
- WISP2/CCN5 revealed as a potential diagnostic biomarker for endometriosis based on machine learning and single-cell transcriptomic analysis 2025
- Integration of Single Cell and Bulk RNA-Sequencing Reveals Key Genes and Immune Cell Infiltration to Construct a Predictive Model and Identify Drug Targets in Endometriosis 2025
- Clinical efficacy and safety of Chinese patent medicines combined with hormonal therapy for endometriosis after laparoscopic surgery: A Bayesian network meta-analysis 2025
- Clinical Presentation, Laparoscopic Findings, and Therapeutic Aspects of Endometriosis in Patients Undergoing Laparoscopy at the Yaound&#233; Gyneco-Obstetric and Pediatric Hospital 2025
- Interobserver Reproducibility of Two Endometriosis Scoring Systems: A Multicentre Observational Prospective Study 2025
- Optimizing Patient Experiences and Outcomes: Proposal to Develop an Endometriosis Care Quality Collaborative in the United States 2025
- Unraveling the role of lncRNA in Endometriosis-Associated immune system Dysregulation: Exploring the intricate immunological changes and disrupted signaling pathways 2025
- Perfil clínico e epidemiológico de pacientes portadoras de endometriose de um serviço ginecológico do Espírito Santo 2025
- The Gut–Endometriosis Axis: Genetic Mechanisms and Public Health Implications 2025
- Immunocompetent mouse models of endometriosis: a systematic review and meta-analysis 2025
- Endometriosis and autoimmunity 2025
- Identifying serum microRNAs as biomarkers for endometriosis in adolescents and young adults 2025
- Early-life environmental exposures and the risk of endometriosis/adenomyosis in the NutriNet-Santé cohort 2025
- Rank Matrix Approach for Endometriosis: Integrating Data and Constructing Diagnostic Models 2024
- Additional file 1 of PARP-1, EpCAM, and FRα as potential targets for intraoperative detection and delineation of endometriosis: a quantitative tissue expression analysis 2024
- Abordagem atual da endometriose: implicações patogênicas e terapêuticas 2024
- A systematic literature review on patient-reported outcome domains and measures in nonsurgical efficacy trials related to chronic pain associated with endometriosis: an urgent call to action 2024
- Anthropometric characteristics and features of the systemic inflammatory response in patients with endometriosis 2024
- Surgery for Severe Endometriosis and ART Outcome and Effect of Time Interval Between Surgery and FET 2024
- Dysmenorrhea and endometriosis in the adolescent female 2024
- Additional file 2 of PARP-1, EpCAM, and FRα as potential targets for intraoperative detection and delineation of endometriosis: a quantitative tissue expression analysis 2024
- Additional file 1 of PARP-1, EpCAM, and FRα as potential targets for intraoperative detection and delineation of endometriosis: a quantitative tissue expression analysis 2024
- The Value of CA125 and CA19-9 in the Diagnosis of Stage Ⅲ and Ⅳ Endometriosis 2024
- Evolution of endometriosis research: A comprehensive analysis of research designs and topics over the last 15 years 2024
- Diet in Prevention and Treatment of Endometriosis: Current State of Knowledge 2024
- A comprehensive multiplatform metabolomic analysis reveals alterations of 2-hydroxybutyric acid among women with deep endometriosis related to the pesticide trans-nonachlor 2024
- Additional file 3 of PARP-1, EpCAM, and FRα as potential targets for intraoperative detection and delineation of endometriosis: a quantitative tissue expression analysis 2024
- Impact of Endometriosis Surgery on In Vitro Fertilization/Intracytoplasmic Sperm Injection Outcomes: a Systematic Review and Meta-analysis 2024
- Additional file 4 of PARP-1, EpCAM, and FRα as potential targets for intraoperative detection and delineation of endometriosis: a quantitative tissue expression analysis 2024
- Reproductive outcome after in vitro fertilization in endometriosis – key factors and implications 2024
- Efficacy and safety of eliapixant in endometriosis-associated pelvic pain: the randomized, placebo-controlled phase 2b SCHUMANN study 2024
- Additional file 3 of PARP-1, EpCAM, and FRα as potential targets for intraoperative detection and delineation of endometriosis: a quantitative tissue expression analysis 2024
- Circulating microRNAs as Non-Invasive Biomarkers in Endometriosis Diagnosis—A Systematic Review 2024
- Uncovering moderators of pain perception by women with endometriosis from Latin America and Spain: the roles of sociodemographics, racial self-identity, and pain catastrophizing 2024
- Endometriosis, Pain, and Related Psychological Disorders: Unveiling the Interplay among the Microbiome, Inflammation, and Oxidative Stress as a Common Thread 2024
- Assessing the Utility of artificial intelligence in endometriosis: Promises and pitfalls 2024
- The Perspectives of Māori and Pasifika Mate Kirikōpū (Endometriosis) Patients in Aotearoa New Zealand 2024
- Additional file 1 of Efficacy and safety of eliapixant in endometriosis-associated pelvic pain: the randomized, placebo-controlled phase 2b SCHUMANN study 2024
- Additional file 2 of PARP-1, EpCAM, and FRα as potential targets for intraoperative detection and delineation of endometriosis: a quantitative tissue expression analysis 2024
- Additional file 4 of PARP-1, EpCAM, and FRα as potential targets for intraoperative detection and delineation of endometriosis: a quantitative tissue expression analysis 2024
- Additional file 1 of Efficacy and safety of eliapixant in endometriosis-associated pelvic pain: the randomized, placebo-controlled phase 2b SCHUMANN study 2024
- The Comparative Invasiveness of Endometriotic Cell Lines to Breast and Endometrial Cancer Cell Lines 2023
- Endometriosis research priorities in Australia 2023
- Users' Concerns About Endometriosis on Social Media: Sentiment Analysis and Topic Modeling Study 2023
- PARP-1, EpCAM, and FRα as potential targets for intraoperative detection and delineation of endometriosis: a quantitative tissue expression analysis 2023
Source provenance
- europepmc
- last seen: 2026-06-13T06:22:48.782012+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:21:00.404924+00:00