Electroacupuncture alleviates endometriosis by suppressing ferroptosis in murine ectopic and eutopic endometria via the Nrf2 pathway

Yan Zan; Yu Zhuang; Qian Zhu; Xiaoquan Huang; Junwei Li; Liangjun Xia; Youbing Xia

doi:10.1016/j.rbmo.2026.105633

Electroacupuncture alleviates endometriosis by suppressing ferroptosis in murine ectopic and eutopic endometria via the Nrf2 pathway

Yan Zan, Yu Zhuang, Qian Zhu, Xiaoquan Huang, Junwei Li, Liangjun Xia, Youbing Xia

In: Reproductive BioMedicine Online · 2026 · vol. 53(2) , pp. 105633 · doi:10.1016/j.rbmo.2026.105633 · PMID:42155249 · W7128926107

article OA: closed CC0

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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Electroacupuncture treatment suppressed ferroptosis in ectopic and eutopic uterine tissues of mice by activating the Nrf2 pathway, thereby alleviating endometriosis.

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endometriosis

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References (48)

Biochemical Characterization of Peritoneal Fluid in Women during the Menstrual Cycle* via openalex
Can Endometriosis-Related Oxidative Stress Pave the Way for New Treatment Targets? via openalex
Cellular Components Contributing to Fibrosis in Endometriosis: A Literature Review via openalex
Clinical diagnosis of endometriosis: a call to action via openalex
Cytokines, Angiogenesis, and Extracellular Matrix Degradation are Augmented by Oxidative Stress in Endometriosis via openalex
Double-edged roles of ferroptosis in endometriosis and endometriosis-related infertility via openalex
Early Endometriosis in Females Is Directed by Immune-Mediated Estrogen Receptor α and IL-6 Cross-Talk via openalex
Endometrial expression and in vitro modulation of the iron transporter divalent metal transporter-1: implications for endometriosis via openalex
Endometrial stromal cells treated by tumor necrosis factor‐α stimulate macrophages polarized toward M2 via interleukin‐6 and monocyte chemoattractant protein‐1 via openalex
Endometriosis: A Disease of Oxidative Stress? via openalex
Endometriosis: The Role of Iron Overload and Ferroptosis via openalex
Endometriotic disease: the role of peritoneal fluid via openalex
Huayu Jiedu Fang Protects Ovarian Function in Mouse with Endometriosis Iron Overload by Inhibiting Ferroptosis via openalex
Iron overload increases the sensitivity of endometriosis stromal cells to ferroptosis via a PRC2-independent function of EZH2 via openalex
Iron storage is significantly increased in peritoneal macrophages of endometriosis patients and correlates with iron overload in peritoneal fluid via openalex
Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity via openalex
Platelets drive smooth muscle metaplasia and fibrogenesis in endometriosis through epithelial–mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation via openalex
Reimagining Endometriosis via openalex
Research Priorities for Endometriosis: Recommendations From a Global Consortium of Investigators in Endometriosis via openalex
Rethinking mechanisms, diagnosis and management of endometriosis via openalex
Smooth muscle metaplasia and innervation in interstitium of endometriotic lesions related to pain via openalex
Targeting Oxidative Stress Involved in Endometriosis and Its Pain via openalex
World Endometriosis Society consensus on the classification of endometriosis via openalex
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W2947494849 via openalex
W3134885188 via openalex
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Source provenance

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openalex: last seen: 2026-06-04T00:00:01.174412+00:00

License: CC0 · commercial use OK

[1] Biochemical Characterization of Peritoneal Fluid in Women during the Menstrual Cycle* via openalex

[2] Can Endometriosis-Related Oxidative Stress Pave the Way for New Treatment Targets? via openalex

[3] Cellular Components Contributing to Fibrosis in Endometriosis: A Literature Review via openalex

[4] Clinical diagnosis of endometriosis: a call to action via openalex

[5] Cytokines, Angiogenesis, and Extracellular Matrix Degradation are Augmented by Oxidative Stress in Endometriosis via openalex

[6] Double-edged roles of ferroptosis in endometriosis and endometriosis-related infertility via openalex

[7] Early Endometriosis in Females Is Directed by Immune-Mediated Estrogen Receptor α and IL-6 Cross-Talk via openalex

[8] Endometrial expression and in vitro modulation of the iron transporter divalent metal transporter-1: implications for endometriosis via openalex

[9] Endometrial stromal cells treated by tumor necrosis factor‐α stimulate macrophages polarized toward M2 via interleukin‐6 and monocyte chemoattractant protein‐1 via openalex

[10] Endometriosis: A Disease of Oxidative Stress? via openalex

[11] Endometriosis: The Role of Iron Overload and Ferroptosis via openalex

[12] Endometriotic disease: the role of peritoneal fluid via openalex

[13] Huayu Jiedu Fang Protects Ovarian Function in Mouse with Endometriosis Iron Overload by Inhibiting Ferroptosis via openalex

[14] Iron overload increases the sensitivity of endometriosis stromal cells to ferroptosis via a PRC2-independent function of EZH2 via openalex

[15] Iron storage is significantly increased in peritoneal macrophages of endometriosis patients and correlates with iron overload in peritoneal fluid via openalex

[16] Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity via openalex

[17] Platelets drive smooth muscle metaplasia and fibrogenesis in endometriosis through epithelial–mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation via openalex

[18] Reimagining Endometriosis via openalex

[19] Research Priorities for Endometriosis: Recommendations From a Global Consortium of Investigators in Endometriosis via openalex

[20] Rethinking mechanisms, diagnosis and management of endometriosis via openalex

[21] Smooth muscle metaplasia and innervation in interstitium of endometriotic lesions related to pain via openalex

[22] Targeting Oxidative Stress Involved in Endometriosis and Its Pain via openalex

[23] World Endometriosis Society consensus on the classification of endometriosis via openalex

[24] W4406185895 via openalex

[25] W4408370664 via openalex

[26] W3198631777 via openalex

[27] W2085103300 via openalex

[28] W2096022216 via openalex

[29] W2533876757 via openalex

[30] W2754055756 via openalex

[31] W2794139372 via openalex

[32] W2892710900 via openalex

[33] W2904201699 via openalex

[34] W2914574872 via openalex

[35] W2947494849 via openalex

[36] W3134885188 via openalex

[37] W3135203598 via openalex

[38] W1969018878 via openalex

[39] W3216458432 via openalex

[40] W4234160457 via openalex

[41] W4281944024 via openalex

[42] W4293004208 via openalex

[43] W4318305673 via openalex

[44] W4318827784 via openalex

[45] W4320481657 via openalex

[46] W4401471986 via openalex

[47] W4405388972 via openalex

[48] W4406058109 via openalex