A Novel Mouse Model of Endometriosis Mimics Human Phenotype and Reveals Insights into the Inflammatory Contribution of Shed Endometrium
This study developed a novel mouse model of endometriosis that successfully mimics human disease characteristics and provides insights into the inflammatory role of shed endometrial tissue.
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Cited by (50)
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- Harnessing the CD16-PI3Kγ axis in peritoneal CD14hi macrophages: A transformative approach to endometriosis management 2025
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- Induction of menstruation in mice reveals the regulation of menstrual shedding 2025
- Endometrial diseases: a summary of small experimental animal model 2025
- Burrowing behavior is a potential non-invasive proxy for lesion development in a syngeneic murine model of endometriosis 2025
- C57BL/6J mice best recapitulate fibrosis and inflammatory pathophysiology in syngeneic mouse model of endometriosis 2025
- Induction of Endometriosis in a Menstruating Mouse Model (Mus musculus): A Translational Animal Disease Model 2025
- MCP-1 promotes ILK phosphorylation at Ser246 during endometriosis development and affects the pregnancy outcome 2025
- Modelling menstruation in the common mouse: a narrative review 2025
- Kynurenine monooxygenase blockade reduces endometriosis-like lesions, improves visceral hyperalgesia, and rescues mice from a negative behavioural phenotype in experimental endometriosis 2024
- High-fat diets promote peritoneal inflammation and augment endometriosis-associated abdominal hyperalgesia 2024
- Western diet promotes endometriotic lesion growth in mice and induces depletion of Akkermansia muciniphila in intestinal microbiota 2024
- Emerging bioengineering breakthroughs in precision diagnosis and therapy for endometriosis and adenomyosis 2024
- MCP-1 exerts the inflammatory response via ILK activation during endometriosis pathogenesis 2024
- Emerging Trends in Nanotechnology for Endometriosis: Diagnosis to Therapy 2024
- Additional file 2 of Endometriosis leads to central nervous system-wide glial activation in a mouse model of endometriosis 2024
- Kynurenine monooxygenase blockade reduces endometriosis-like lesions, improves visceral hyperalgesia, and rescues mice from a negative behavioural phenotype in experimental endometriosis 2024
- eLife Assessment: Kynurenine monooxygenase blockade reduces endometriosis-like lesions, improves visceral hyperalgia, and rescues mice from a negative behavioural phenotype in experimental endometriosis 2024
- Spatial Transcriptomic Analysis Identifies Epithelium-Macrophage Crosstalk in Endometriotic Lesions 2024
- The uterine secretome initiates growth of gynecologic tissues in ectopic locations 2024
- Reviewer #1 (Public Review): Kynurenine monooxygenase blockade reduces endometriosis-like lesions, improves visceral hyperalgia, and rescues mice from a negative behavioural phenotype in experimental endometriosis 2024
- Kynurenine monooxygenase blockade reduces endometriosis-like lesions, improves visceral hyperalgia, and rescues mice from a negative behavioural phenotype in experimental endometriosis 2024
- Investigating endometriosis development and endometriosis-related pain over time and in relation to estrogen in a laparoscopic mouse model 2024
- Preclinical testing of RRx-001 in mouse models of experimental endometriosis reveals promising therapeutic impacts 2024
- Unveiling the fibrotic puzzle of endometriosis: An overlooked concern calling for prompt action 2024
- Unveiling the fibrotic puzzle of endometriosis: An overlooked concern calling for prompt action 2024
- Kynurenine monooxygenase blockade reduces endometriosis-like lesions, improves visceral hyperalgesia, and rescues mice from a negative behavioural phenotype in experimental endometriosis 2024
- Additional file 2 of Endometriosis leads to central nervous system-wide glial activation in a mouse model of endometriosis 2024
- Endometriotic tissue fragments are viable after cryopreservation in an <i>ex vivo</i> tissue model recapitulating the fibrotic microenvironment 2024
- The Known, the Unknown and the Future of the Pathophysiology of Endometriosis 2024
- Single-cell analysis identifies distinct macrophage phenotypes associated with pro-disease and pro-resolving functions in the endometriotic niche 2024
- Role of neuropeptides in patients with endometriosis: a literature review 2024
- Reviewer #2 (Public Review): Kynurenine monooxygenase blockade reduces endometriosis-like lesions, improves visceral hyperalgia, and rescues mice from a negative behavioural phenotype in experimental endometriosis 2024
- PAK5-mediated PKM2 phosphorylation is critical for anaerobic glycolysis in endometriosis 2024
- Endometriosis leads to central nervous system-wide glial activation in a mouse model of endometriosis 2023
- Pre-clinical Models of Endometriosis: A Focus on Chronic Pain 2023
- Features of the clinical picture and severity of pain syndrome in girls with genital endometriosis on the background of conservative therapy of the disease in adolescence 2023
- Estrobolome dysregulation is associated with altered immunometabolism in a mouse model of endometriosis 2023
- MicroRNAs in Endometriosis: Insights into Inflammation and Progesterone Resistance 2023
- The Sphingosine 1-Phosphate Axis: an Emerging Therapeutic Opportunity for Endometriosis 2023
- Precision-engineered biomimetics: the human fallopian tube 2023
- Proposal for targeted, neo-evolutionary-oriented, secondary prevention of early-onset endometriosis and adenomyosis. Part I: pathogenic aspects 2023
- Fertilidade, resultados gestacionais e perinatais relacionados a endometriose experimental em modelo murino 2023
- <scp><i>KRAS</i></scp> mutations and endometriosis burden of disease 2023
- Applications of nanomaterials in endometriosis treatment 2023
- Uterine secretome initiates growth of gynecologic tissues in ectopic locations 2023
- Optimizing a Translational Mouse Model of Endometriosis 2023
- Modeling Endometrium Biology and Disease 2022
- Advances in targeting estrogen synthesis and receptors in patients with endometriosis 2022
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