The prevalence of spontaneous endometriosis in the baboon (Papio anubis, Papio cynocephalus) increases with the duration of captivity

Thomas D’Hooghe, Thomas D'Hooghe, T M D'Hooghe, Charanjit S. Bambra, C S Bambra, Inge De Jonge, I De Jonge, Johan M. Lauweryns, J M Lauweryns, Philippe R. Koninckx, P R Koninckx
Acta obstetricia et gynecologica Scandinavica · 1996 · vol. 75(2) , pp. 98–101 · doi:10.3109/00016349609033298 · PMID:8604618 · W2067216543
article OA: closed CC0 ⤵ 44 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This study found that the prevalence of endometriosis in baboons increased with the duration of captivity, suggesting a link to uninterrupted menstrual cycles and potential stress.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

BACKGROUND: It is not known whether stress affects the prevalence of endometriosis in women. Baboons with spontaneous endometriosis may be interesting models to study the human disease. For baboons, living in captivity is a period of chronic stress without continuous exposure to pregnancy. This study was done to compare the prevalence of endometriosis between baboons recently captured in the wild and those living in captivity for several years. METHODS: A diagnostic laparoscopy was performed for screening endometriosis and obtaining biopsies in 104 female baboons including animals that had been captured in the wild less than 1 year ago (n=52, Group I), primates that had been living in captivity for one to two years (n=30, Group II) and animals that had been captured for more than two years (n=22, Group III). RESULTS: The prevalence of clinical and biopsy-proven endometriosis in all baboons was 17% and 12%, respectively. Clinical endometriosis was found more frequently in group III (32%) than in group II (17%) or group I (11%). The prevalence of biopsy-proven endometriosis was also significantly higher in group III (27%) than in groups I and II combined (8%, p=0.03). CONCLUSIONS: The results indicate that the prevalence of endometriosis increases with the time spent in captivity. This trend may be explained by more menstrual cycles uninterrupted by pregnancy in captive than in wild baboons, and possibly also by age-related factors or by captivity-associated stress.

My notes (saved in your browser only)

Condition tags

mesh:D004715endometriosis

MeSH descriptors

Animals, Laboratory Animals, Wild Endometriosis Papio Papio Primate Diseases Age Factors Animals Chronic Disease Disease Models, Animal Endometriosis Endometriosis Endometriosis Female Housing, Animal Housing, Animal Prevalence Primate Diseases Primate Diseases Stress, Psychological

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (16)

Cited by (44)

Source provenance

europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:11:08.331550+00:00
License: CC0 · commercial use OK