Morphological Characteristics of Spontaneous Endometriosis in the Baboon (Papio anubis and Papio cynocephalus)
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Abstract
The histopathology of spontaneous endometriosis was studied on 20 pelvic implants biopsied at laparoscopy in 15 healthy baboons. Endometriosis was confirmed by histopathology in 10 of these animals (66%). Typical (n = 3) and subtle (n = 13) endometriotic lesions were confirmed by histopathology in 100 and 61%, respectively. Suspected disease-bearing lesions (n = 4) were confirmed in 50%. Implants could be classified as active (n = 5), inactive (n = 3), atrophic (n = 2) or stromal endometriosis (n = 3). The histological findings for typical and subtle implants were similar to those reported in humans.
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Cited by (21)
- The Known, the Unknown and the Future of the Pathophysiology of Endometriosis 2024
- Is retrograde menstruation a universal, recurrent, physiological phenomenon? A systematic review of the evidence in humans and non-human primates 2024
- The Natural History of Spontaneously Occurred Endometriosis in Cynomolgus Monkeys by Monthly Follow-Up Laparoscopy for Two Years 2020
- Icon immunoconjugate treatment results in regression of red lesions in a non-human primate (Papio anubis) model of endometriosis 2018
- Endometriosis and its global research architecture: an in-depth density-equalizing mapping analysis 2016
- Translational In Vivo Models for Women’s Health: The Nonhuman Primate Endometrium—A Predictive Model for Assessing Steroid Receptor Modulators 2015
- Estrogen-Induced CCN1 Is Critical for Establishment of Endometriosis-Like Lesions in Mice 2014
- Baboon Model for Endometriosis 2009
- Nonhuman Primate Models for Translational Research in Endometriosis 2009
- Baboon Model for the Study of Endometriosis 2007
- "Endometriose do trato gastrointestinal: correlações clínicas e laparoscópicas; papel da corrida dos órgãos peritoneais na endometriose (COPE)" 2005
- Animal Studies in Endometriosis: A Review 2004
- Animal Models for Research on Endometriosis 2003
- Record review of baboons with histologically confirmed endometriosis in a large established colony 2003
- Biases in the endometriosis literature 1998
- Clinical relevance of the baboon as a model for the study of endometriosis 1997
- Risk factors for endometriosis in the rhesus monkey (Macaca mulatta): a case-control study 1997
- Serial laparoscopies over 30 months show that endometriosis in captive baboons (Papio anubis, Papio cynocephalus) is a progressive disease 1996
- The prevalence of spontaneous endometriosis in the baboon (Papio anubis, Papio cynocephalus) increases with the duration of captivity 1996
- Development of spontaneous endometriosis in baboons 1996
- The Puzzle of Endometriosis 1995
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