Endometriosis involving the ileocaecal junction with regional lymph node involvement in the baboon—striking pathological finding identical between the human and the baboon: A Case Report

B F Barrier, Breton F. Barrier, Edward J. Dick, E J Dick, Stephanie D. Butler, S D Butler, G B Hubbard, Gene B. Hubbard
Human Reproduction · 2006 · vol. 22(1) , pp. 272–274 · doi:10.1093/humrep/del352 · PMID:16959811 · W2151085465
article OA: bronze CC0 ⤵ 10 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

A baboon spontaneously developed endometriosis of the ileocaecal junction and lymph nodes, mirroring human pathology and supporting the baboon's validity as an endometriosis model.

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Abstract

The baboon is an established model for endometriosis research. This report describes the occurrence of spontaneous endometriosis involving the ileocaecal junction and associated regional lymph nodes in the baboon. All endometriotic foci lacked the nuclear atypia, abnormal mitotic activity and altered nuclear-to-cytoplasmic ratio typical of malignancy. These findings are identical to reports in the human in which ileocaecal and colonic endometriosis is associated with endometriosis in pericolonic and mesenteric lymph nodes. The similarity between baboon and human colonic endometriosis in both location and pathology is striking and lends further evidence supporting the validity of the baboon as a model for human endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Colonic Diseases Endometriosis Ileocecal Valve Lymph Nodes Animals Colon Colonic Diseases Disease Models, Animal Endometriosis Endometriosis Female Humans Ileocecal Valve Lymph Nodes Papio

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References (21)

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