Modèles animaux dans la recherche expérimentale sur l’endométriose

Colette S, S. Colette, Donnez J, Jacques Donnez, J. Donnez
Gynecologie, obstetrique & fertilite · 2012 · vol. 40(9) , pp. 494–496 · doi:10.1016/j.gyobfe.2012.07.009 · PMID:22901780 · W2051005382
review OA: closed CC0 ⤵ 7 in-corpus citations
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This paper reviews animal models used in experimental endometriosis research, discussing their utility and limitations.

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Abstract

Sampson's menstrual reflux theory is commonly used to explain the origin of endometriotic lesions in women. However, their pathogenesis remains largely unknown. Validated research models need to be developed with the aim of studying mechanisms by which endometrial cells from menstrual reflux implant and grow, and investigating if potential new markers or molecules could be envisaged as diagnostic or therapeutic tools. The present review looks at the different existing murine and non-human primate models of endometriosis, and evaluates their principal uses.

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Condition tags

endometriosis

MeSH descriptors

Disease Models, Animal Endometriosis Endometriosis Animals Cricetinae Endometrium Endometrium Female Humans Menstruation Mice Primates Rabbits Rats Transplantation, Heterologous

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (28)

Cited by (7)

Source provenance

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License: CC0 · commercial use OK