Evolution of spontaneous endometriosis in the baboon (Papio anubis, Papio cynocephalus) over a 12-month period
article
OA: closed
CC0
⤵ 41 in-corpus citations
AI-generated summary
This study observed the natural progression of spontaneous endometriosis in baboons over a twelve-month period.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
To document the spontaneous evolution of endometriosis, a repeat laparoscopy was performed in 11 baboons after 10 and/or 12 months. The mean number of endometriotic lesions had increased significantly after 10 months (P less than 0.02) because of a high proportion of new lesions (82%). These implants were mainly subtle (67%) and localized on the uterine peritoneum (58%). Progression of endometriosis did not go beyond revised AFS stage I. Additionally, repeat laparoscopy in 10 baboons with an initially normal pelvis showed an endometriosis incidence of 70% after 10 to 12 months. Remodeling of the lesions was apparent in both groups after 12 months. These results suggest that endometriosis is moderately progressive in the baboon. It is possible that multiple laparoscopies could favor the development of endometriosis.
My notes (saved in your browser only)
Condition tags
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (6)
- Impact of gestrinone on the course of asymptomatic endometriosis. via openalex
- Prevalence and Laparoscopic Appearance of Spontaneous Endometriosis in the Baboon (Paplo Anubis, Papio Cynocephalus)1 via openalex
- The impact of treatment on the natural history of endometriosis via openalex
- W2291960606 via openalex
- W2410385631 via openalex
- W2477008945 via openalex
Cited by (41)
- The Known, the Unknown and the Future of the Pathophysiology of Endometriosis 2024
- What We Have Learned from Animal Models to Understand the Etiology and Pathology of Endometrioma-Related Infertility 2022
- Evidence in Support for the Progressive Nature of Ovarian Endometriomas 2020
- The Natural History of Spontaneously Occurred Endometriosis in Cynomolgus Monkeys by Monthly Follow-Up Laparoscopy for Two Years 2020
- Icon immunoconjugate treatment results in regression of red lesions in a non-human primate (Papio anubis) model of endometriosis 2018
- Spontaneous endometriosis in cynomolgus monkeys as a clinically relevant experimental model 2018
- Endometriosis and its global research architecture: an in-depth density-equalizing mapping analysis 2016
- Endometriosis 2015
- Estrogen-Induced CCN1 Is Critical for Establishment of Endometriosis-Like Lesions in Mice 2014
- The role of the peritoneum in the pathogenesis of endometriosis 2013
- Aromatase inhibitor treatment limits progression of peritoneal endometriosis in baboons 2012
- Lesion kinetics in a non-human primate model of endometriosis 2012
- Pathophysiological factors and genetic association in endometriosis 2011
- Endometriosis 2010
- Baboon Model for Endometriosis 2009
- Endometriosis and ovarian reserve : Inflammation and prognostic markers 2008
- Development and evaluation of two mouse models for endometriosis focused on the involvement of the immune system in endometriosis establishment 2008
- Baboon Model for the Study of Endometriosis 2007
- Treatment with anti-TNF monoclonal antibody (c5N) reduces the extent of induced endometriosis in the baboon 2006
- The Baboon as an Appropriate Model for the Study of Multifactoral Aspects of Human Endometriosis 2005
- The effect of endometriosis, cycle stage, lymphocyte suppression and pregnancy on CA-125 levels in peritoneal fluid and serum in baboons 2005
- Animal Models for Research on Endometriosis 2003
- Record review of baboons with histologically confirmed endometriosis in a large established colony 2003
- The potential role of exposure to environmental toxicants in the pathophysiology of endometriosis 2002
- Laparoscopic Surgery for Endometriosis: A Long Term Follow‐Up 2000
- Pelvic inflammation induced by diagnostic laparoscopy in baboons 1999
- Could tight garments cause endometriosis? 1999
- Biases in the endometriosis literature 1998
- Clinical relevance of the baboon as a model for the study of endometriosis 1997
- Peritoneal Cellular Immunity and Endometriosis 1997
- Risk factors for endometriosis in the rhesus monkey (Macaca mulatta): a case-control study 1997
- Continuous Exposure to 2,3,7,8-Tetrachlorodibenzo- <i>P</i> -Dioxin Inhibits the Growth of Surgically Induced Endometriosis in the Ovariectomized Mouse Treated with high Dose Estradiol 1997
- The prevalence of spontaneous endometriosis in the baboon (Papio anubis, Papio cynocephalus) increases with the duration of captivity 1996
- Benefit of in vitro fertilization treatment for endometriosis-associated infertility 1996
- Serial laparoscopies over 30 months show that endometriosis in captive baboons (Papio anubis, Papio cynocephalus) is a progressive disease 1996
- Development of spontaneous endometriosis in baboons 1996
- Peritoneal fluid volume and steroid hormone concentrations in baboons with and without either spontaneous minimal/mild endometriosis or the luteinized unruptured follicle syndrome 1995
- Rationale for Surgical Treatment of Endometriosis 1995
- Pain and infertility – a rationale for different treatment approaches 1995
- Intrapelvic injection of menstrual endometrium causes endometriosis in baboons (Papio cynocephalus and Papio anubis) 1995
- Angiogenic activity of peritoneal fluid from women with endometriosis 1993
Source provenance
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0
· commercial use OK