Benefit of in vitro fertilization treatment for endometriosis-associated infertility

H. Kodama, Kodama H, J Fukuda, Fukuda J, Jun Fukuda, Hiroko Karube, H Karube, Karube H, Matsui T, T Matsui, Toshihiko Matsui, Yasushi Shimizu, Y Shimizu, Shimizu Y, Toshinobu Tanaka, T Tanaka, Tanaka T
Fertility and sterility · 1996 · vol. 66(6) , pp. 974–979 · doi:10.1016/s0015-0282(16)58692-0 · PMID:8941064 · W2339384473
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This study investigated the effectiveness of in vitro fertilization treatment for infertility caused by endometriosis.

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Abstract

ObjectiveTo evaluate the effectiveness of IVF treatment in endometriosis-associated infertility.DesignNonrandom retrospective study.SettingDepartment of Gynecology and Obstetrics, Akita University School of Medicine.Main outcome measure(s)Cumulative pregnancy rate.Patient(s)One hundred eighteen infertile patients in whom diagnosis of endometriosis was established by laparoscopic examination.Intervention(s)The prognoses of 60 patients (IVF group) who started IVF treatment within 6 months after laparoscopy were compared with those of 58 patients who were managed expectantly without IVF treatment during the same period.Result(s)The cumulative conception rates at 36 months after laparoscopy were 62% in the IVF group and 43% in the control group, and the difference was not significant (a log-rank test). For patients > or = 32 years of age, the conception rates were significantly higher in the IVF group (59% versus 29%). A relatively large but nonsignificant difference in the conception rate between the two groups was observed in patients with endometriosis at stages III or IV (52% versus 27%).Conclusion(s)In vitro fertilization treatment provides better prognosis in patients > or = 32 years of age and is recommended for such patients. The benefits of treatment appear to be greater in patients with more advanced stages of endometriosis.

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Fertilization in Vitro Infertility, Female Infertility, Female Adult Aging Aging Endometriosis Endometriosis Evaluation Studies as Topic Female Humans Infertility, Female Pregnancy Rate Prognosis Retrospective Studies

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (34)

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