Angiogenic activity of peritoneal fluid from women with endometriosis

D J Oosterlynck, Oosterlynck DJ, Didier J. Oosterlynck, C Meuleman, Christel Meuleman, Meuleman C, H. Sobis, Sobis H, Vandeputte M, Michel Vandeputte, M Vandeputte, P R Koninckx, Philippe R. Koninckx, Koninckx PR
Fertility and sterility · 1993 · vol. 59(4) , pp. 778–782 · doi:10.1016/s0015-0282(16)55859-2 · PMID:8458496 · W2404389558
article OA: closed CC0 ⤵ 152 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This study investigated the angiogenic activity of peritoneal fluid collected from women with endometriosis.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

ObjectiveTo investigate the presence of angiogenic factors in peritoneal fluid (PF) and follicular fluid (FF).DesignThe PF samples of 48 women with (n = 24) or without (n = 24) endometriosis were investigated. Angiogenesis was assayed using the chorioallantoic membrane of 11-day-old fertilized chicken embryos. Glass fiber prefilters impregnated with the fluids were placed on the chorioallantoic membrane.Main outcome measureThe vascular reaction was analyzed by an independent observer after 72 hours.ResultsThere was a positive reaction in 58.3% of the PF from women with endometriosis and in 12.5% of the women without endometriosis. No correlation was found between the angiogenic response and the severity of endometriosis. The reaction remained after charcoal treatment of the PF. Positive reaction was found in three of six FF samples.ConclusionThe PF of women with endometriosis contain more angiogenic factors than PF from women without endometriosis. This angiogenic activity could be important for the further outgrowth and progression of the lesions.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Angiogenesis Inducing Agents Ascitic Fluid Endometriosis Angiogenesis Inducing Agents Animals Ascitic Fluid Biological Assay Chick Embryo Endometriosis Endometriosis Endometriosis Female Humans Killer Cells, Natural Killer Cells, Natural

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (21)

Cited by (50)

Source provenance

europepmc
last seen: 2026-08-25T06:10:03.373225+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:11:39.448046+00:00
unpaywall
last seen: 2026-08-25T06:41:39.333708+00:00
License: CC0 · commercial use OK