The Impact of Ovarian Endometrioma(s) on ART Outcomes: Retrospective Case Control Study

Emre Pabuçcu, Aslı Yarcı Gürsoy, Hasan Ulubaşoğlu, Özgür Doğuş Demirkıran, Gamze Sinem Çağlar, Recai Pabuçcu
In: Gynecology Obstetrics & Reproductive Medicine · 2016 · vol. 22(2) , pp. 84–89 · doi:10.21613/gorm.2016.63 · W2417280123
article OA: diamond CC0
🔓 Open OA copy Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Women with intact ovarian endometriomas undergoing ART had longer stimulation cycles, higher gonadotropin use, and fewer mature oocytes retrieved, but similar implantation and live birth rates compared to controls.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text ⓘ

This retrospective case-control study compared ART outcomes in 165 women with intact ovarian endometrioma(s) versus 196 matched controls with tubal disease as the sole cause of infertility, using matching for age, BMI, and serum AMH. Although cycle characteristics differed, with the endometrioma group requiring longer stimulation and higher gonadotropin consumption, the key finding was a significantly lower oocyte yield, including fewer mature oocytes and a reduced mature oocyte fraction. Fertilization, implantation, and live birth rates per started cycle did not differ significantly between groups, and cycle cancellation rates were similar. This paper is centrally about endometriosis — it specifically evaluates how ovarian endometrioma(s) affect oocyte quantity and maturity and subsequent ART outcomes.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

OBJECTIVE: To compare oocyte yield of women with intact ovarian endometrioma(s) to those without endometrioma undergoing ART. Secondary outcomes were implantation and live birth rates between the two groups.STUDY DESIGN: Retrospective case-control study was conducted to document eligible cases. A total of 165 women with intact endometrioma(s) (END) were included in the final analysis. Controls were 196 cases with tubal disease as the sole cause of their infertility who underwent ART in the same time period. Cases and controls were matched for age, BMI and serum AMH concentrations. Ovarian stimulation characteristics and pregnancy outcomes including live birth data were documented for both groups.RESULTS: Despite similar demographic characteristics, significantly longer cycle duration and higher amounts of gonadotropin consumption was observed in END group compared to controls (p<0.001). Significantly lower numbers of retrieved oocytes, mature oocytes and mature oocyte fraction (%, no of retrieved/mature) was detected in END group. There was no statistically significant difference in terms of fertilization, implantation and live birth rate per started cycle among groups. Cycle cancellations were also similar.CONCLUSION: In women with intact ovarian endometrioma(s) undergoing ART, oocyte quantity, especially mature oocyte yield was hampered. However, adequate number of mature oocytes, successful fertilization and satisfactory implantation rates might be possible contributing to acceptable live births. Further randomized controlled trials of patients with different sizes of endometrioma(s) would be needed to confirm our conclusions.
Full text 2,309 characters · extracted from oa-doi-fallback · 3 sections · click to expand

Objective

To compare oocyte yield of women with intact ovarian endometrioma(s) to those without endometrioma undergoing ART. Secondary outcomes were implantation and live birth rates between the two groups. STUDY DESIGN: Retrospective case-control study was conducted to document eligible cases. A total of 165 women with intact endometrioma(s) (END) were included in the final analysis. Controls were 196 cases with tubal disease as the sole cause of their infertility who underwent ART in the same time period. Cases and controls were matched for age, BMI and serum AMH concentrations. Ovarian stimulation characteristics and pregnancy outcomes including live birth data were documented for both groups.

Results

Despite similar demographic characteristics, significantly longer cycle duration and higher amounts of gonadotropin consumption was observed in END group compared to controls (p<0.001). Significantly lower numbers of retrieved oocytes, mature oocytes and mature oocyte fraction (%, no of retrieved/mature) was detected in END group. There was no statistically significant difference in terms of fertilization, implantation and live birth rate per started cycle among groups. Cycle cancellations were also similar.

Conclusion

In women with intact ovarian endometrioma(s) undergoing ART, oocyte quantity, especially mature oocyte yield was hampered. However, adequate number of mature oocytes, successful fertilization and satisfactory implantation rates might be possible contributing to acceptable live births. Further randomized controlled trials of patients with different sizes of endometrioma(s) would be needed to confirm our conclusions. Downloads Downloads Published How to Cite Issue Section License All the articles published in GORM are licensed with "Creative Commons Attribution 4.0 License (CC BY 4.0)". This license entitles all parties to copy, share and redistribute all the articles, data sets, figures and supplementary files published in this journal in data mining, search engines, web sites, blogs and other digital platforms under the condition of providing references.

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriomainfertility

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (36)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK