A focus on the distinctions and current evidence of endometriosis in adolescents

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This report reviews the unique clinical and histologic features of adolescent endometriosis, discusses diagnostic methods, and updates current treatment knowledge to reduce diagnostic delays.

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Abstract

Endometriosis (EM) occurring in adolescents presents distinct clinical and histologic characteristics compared to the disease in women. Because the symptoms of EM are nonspecific, often overlapping with those experienced in a range of gynecological and gastrointestinal conditions, the process of reaching a diagnosis of EM is often delayed. The diagnosis of EM is suspected depending on the history and the symptoms and signs, is corroborated by physical examination and imaging techniques, and is finally proved by histological examination of specimens collected during laparoscopy. Currently, there is insufficient evidence to make strong recommendations for management in adolescents who may have EM. This short report reviews some peculiarities of EM in adolescents and provides an update of recent knowledge of the diagnosis and treatment of EM. We hope that the present contribution may help to bring more attention to the clinical diagnosis of EM and consequently aid in decreasing diagnostic delay.

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Condition tags

dysmenorrheaendometriosis

MeSH descriptors

Dysmenorrhea Endometriosis Adolescent Chronic Pain Chronic Pain Delayed Diagnosis Disease Progression Dysmenorrhea Dysmenorrhea Dysmenorrhea Endometriosis Endometriosis Endometriosis Endometriosis Female Humans Incidence Randomized Controlled Trials as Topic Risk Factors Severity of Illness Index

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (76)

Source provenance

crossref
last seen: 2026-08-01T06:38:04.382432+00:00
europepmc
last seen: 2026-09-11T06:15:56.568227+00:00
pubmed
last seen: 2026-05-13T22:19:55.107525+00:00
unpaywall
last seen: 2026-09-11T06:32:28.951138+00:00
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