Laparoscopic Surgery in Adolescent Endometriosis

In: Endometriosis in Adolescents · 2020 · pp. 595–611 · doi:10.1007/978-3-030-52984-0_36 · W3105781087
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Early laparoscopy offers diagnosis and treatment for symptomatic adolescent endometriosis, reducing pain but carrying a risk of recurrence and concerns for fertility.

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This chapter reviews evidence on surgical management in symptomatic adolescents with endometriosis, focusing on indications, operative findings, outcomes, and features that differ from adult disease. It reports that early laparoscopy in adolescents who do not respond to medical treatment, have suspected advanced-stage disease, a questioned diagnosis, or an endometrioma offers both diagnosis and treatment, with substantial proportions showing advanced disease and ovarian endometriomas, though subtle findings may be missed without experience, leading to false-negative diagnoses. The chapter states that laparoscopy is effective for reducing pain but that adolescents have a higher risk of symptom recurrence and may need repeat surgery, and that subfertility concerns correlate with disease severity; it emphasizes that careful follow-up and support are important. This paper is centrally about endometriosis — it specifically discusses laparoscopic surgery in adolescent endometriosis.

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Abstract

The purpose of this chapter is to present the keen reader an updated information and the accumulated evidence on surgery in adolescent endometriosis (EM) and to discuss surgical indications, findings, outcomes, and specific aspects of the disease that relate to surgery. The presenting symptoms and surgical findings somewhat differ from the endometriosis in the adult, contributing to a particularly challenging diagnosis. In the selected population of symptomatic adolescents not responding to medical treatment, a questioned diagnosis, suspected advanced stage disease, or with endometrioma, early laparoscopy has the advantage of diagnosis and treatment (as in some Mullerian anomalies). The full spectrum of disease severity is found, including advanced stage EM in a substantial percent, and ovarian endometrioma cysts, with a special concern for future fertility and special surgical aspects. Subtle surgical findings may be unidentified by the inexperienced surgeon leading to false-negative diagnosis; thus, we strongly encourage video recordings and biopsies. In adolescents, laparoscopy is very effective in reducing pain, bearing in mind a higher risk for symptom recurrence which may lead to repeat surgical intervention. Postoperative follow-up and treatment are crucial to identify and reduce recurrence. Subfertility is an important concern even in this young population, correlated with disease severity. The implications of the medical encounter between caregiver and patient are immense, especially in adolescents, in broad aspects including physical, social, and psychological. It is beneficial to offer a suitable support system as part of a holistic approach. Accordingly, successful and well-timed treatment is much rewarding. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

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Dunselman GA, Vermeulen N, Becker C, Calhaz-Jorge C, D’Hooghe T, De Bie B, Heikimheimo O, Horne AW, Kiesel L, Nap A, Prentice A, Saridogan E, Soriano D, Nelen W. European society of human reproduction and embryology/ ESHRE guideline: management of women with endometriosis. Hum Reprod. 2014;29:400–12. Sarıdoğan E. Adolescent endometriosis. Eur J Obstet Gynecol Reprod Biol. 2017;209:46–9. Yang Y, Wang Y, Yang J, Wang S, Lang J. Adolescent endometriosis in China: a retrospective analysis of 63 cases. J Pediatr Adolesc Gynecol. 2012;25:295–9. Laufer MR, Goitein L, Bush M, Cramer DW, Emans SJ. Prevalence of endometriosis in adolescent girls with chronic pelvic pain not responding to conventional therapy. J Pediatr Adolesc Gynecol. 1997;10:199–202. Lee D-Y, Kim HJ, Yoon BK. Clinical characteristics of adolescent endometrioma. J Pediatr Adolesc Gynecol. 2013;26:117–9. Yeung P Jr, Sinervo K, Winer W, Albee RB Jr. Complete laparoscopic resection in teenagers: is postoperative hormonal suppression necessary? Fertil Steril. 2011;95:1909–12. Audebert A, Lecointre L, Afors K, Koch A, Wattiez A, Akladios C. Adolescent endometriosis: report of a series of 55 cases with a focus on clinical presentation and long-term issues. J Minim Invasive Gynecol. 2015;22(5):834–40. https://doi.org/10.1016/j.jmig.2015.04.001 Stuparich MA, Donnellan NM, Sanfilippo JS. Endometriosis in the adolescent patient. Semin Reprod Med. 2017;35:102–9. Janssen EB, Rijkers AC, Hoppenbrouwers K, Meuleman C, D’Hooghe TM. Prevalence of endometriosis diagnosed by laparoscopy in adolescents with dysmenorrhea or chronic pelvic pain: a systematic review. Hum Reprod Update. 2013;19:570–82. Reese KA, Reddy S, Rock JA. Endometriosis in an adolescent population: the Emory experience. J Pediatr Adolesc Gynecol. 1996;9:125–8. Simpson JL, Elias S, Malinak LR, Buttram VC Jr. Heritable aspects of endometriosis. Genetic studies. Am J Obstet Gynecol. 1980;137:327–31. Dun EC, Kho KA, Morozov VV, Kearney S, Zurawin JL, Nezhat CH. Endometriosis in adolescents. JSLS. 2015;19(2):e2015.00019. Roman JD. Adolescent endometriosis in the Waikato region of New Zealand – a comparative cohort study with a mean follow-up time of 2.6 years. Aust N Z J Obstet Gynaecol. 2010;50:179–83. Treloar SA, Bell TA, Nagle CM, Purdie DM, Green AC. Early menstrual characteristics associated with subsequent diagnosis of endometriosis. Am J Obstet Gynecol. 2010;202:534–6. Nnoaham KE, Webster P, Kumbang J. Is early age at menarche a risk factor for endometriosis? A systematic review and meta-analysis of case-control studies. Fertil Steril. 2012;98:702–12. Sutton CJ, Ewen SP, Whitelaw N, Haines P. Prospective, randomized, double-blind, controlled trial of laser laparoscopy in the treatment of pelvic pain associated with minimal, mild, and moderate endometriosis. Fertil Steril. 1994;62:696–700. Greene R, Stratton P, Cleary SD, Ballweg ML, Sinaii N. Diagnostic experience among 4,334 women reporting surgically diagnosed endometriosis. Fertil Steril. 2009;91:32–9. Brosens I, Gordts S, Benagiano G. Endometriosis in adolescents is a hidden, progressive and severe disease that deserves attention, not just compassion. Hum Reprod. 2013;28:2026–31. Meuleman C, Tomassetti C, Gaspar Da Vitoria Magro M, Van Cleynenbreugel B, D’Hoore A. Laparoscopic treatment of endometriosis. Minerva Ginecol. 2013;65:125–42. Fassbender A, Dorien O, De Moor B, Waelkens E, Meuleman C, Tomassetti C, et al. Biomarkers of endometriosis. Endometr Pathog Treat. Elsevier Inc. 2014;99:321–39. Powell J. The approach to chronic pelvic pain in the adolescent. Obstet Gynecol Clin North Am. Elsevier Inc. 2014;41:343–55. Sanfilippo JS, Wakim NG, Schikler KN, Yussman MA. Endometriosis in association with Uterine anomaly. Am J Obstet Gynecol. 1986;154:39–43. Olive DL, Schwartz LB. Endometriosis. N Engl J Med. 1993;328:1759–69. Gambone JC, Mittman BS, Munro MG, Scialli AR, Winkel CA, Chronic Pelvic Pain/Endometriosis Working Group. Consensus statement for the management of chronic pelvic pain and endometriosis: proceedings of an expert-panel consensus process. Fertil Steril. 2002;78:961–72. Canis M, Donnez JG, Guzick DS, Halme JK, Rock JA, Schenken RS, Vernon MW. Revised American Society for Reproductive Medicine classification of endometriosis. Fertil Steril. 1996;67:817–21. Benagiano G, Guo S, Puttemans P, Gordts S, Brosens I. Progress in the diagnosis and management of adolescent endometriosis: an opinion. Reprod Biomed Online. 2018;36:102–14. Dowlut-McElroy T, Strickland JL. Endometriosis in adolescent. Curr Opin Obstet Gynecol. 2017;29:306–9. Stavroulis AI, Saridogan E, Creighton SM, Cutner AS. Laparoscopic treatment of endometriosis in teenagers. Eur J Obstet Gynecol Reprod Boil. 2006;125:248–50. Davis GD, Thillet E, Lindemann J. Clinical characteristics of adolescent endometriosis. J Adolesc Health. 1993;14:362–8. Vicino M, Parazzini F, Cipriani S, Frontino G. Endometriosis in young women: the experience of GISE. J Pediatr Adolesc Gynecol. 2010;23:223–5. Smorgick N, As-Sanie S, Marsh CA, Smith YR, Quint EH. Advanced stage endometriosis in adolescents and young women. J Pediatr Adolesc Gynecol. 2014;27:320–3. Kitajima M, Defrre S, Dolmans M. Endometriomas as a possible cause of reduced ovarian reserve in women with endometriosis. Fertil Steril. 2011;96:685–91. Nezhat F, Nezhat C, Allan CJ, Metzger DA, Sears DL. Clinical and histologic classification of endometriomas. Implications for a mechanism of pathogenesis. J Reprod Med. 1992;37:771–6. Redwine DB. Ovarian endometriosis: a marker for more extensive pelvic and intestinal disease. Fertil Steril. 1999;72:310–5. Gordts S, Puttemans P, Gordts S, Brosens I. Ovarian endometrioma in the adolescent: a plea for early-staging diagnosis and full surgical treatment. Gynecol Surg. 2015;12:21–30. de Sanctis V, Matalliotakis M, Soliman AT, Elsefdy H, Di Maio S, Fiscina B. A focus on the distinctions and current evidence of endometriosis in adolescents. Best Pract Res Clin Obstet Gynaecol. 2018;51:138–50. Chapron C, Pietin-Vialle C, Borghese B, Davy C, Foulot H, Chopin N. Associated ovarian endometrioma is a marker for greater severity of deeply infiltrating endometriosis. Fertil Steril. 2009;92:453–7. Working group of ESGE ESHRE and WES, Saridogan E, Becker CM, Feki A, Grimbizis GF, Hummelshoj L, et al. Recommendations for the surgical treatment of endometriosis-part 1: ovarian endometrioma. Gynecol Surg. 2017;14:27. Cranney R, Condous G, Reid S. An update on the diagnosis, surgical management, and fertility outcomes for women with endometrioma. Acta Obstet Gynecol Scand. 2017;96:633–43. Roman H, Auber M, Bourdel N, Martin C, Marpeau L, Puscasiu L. Postoperative recurrence and fertility after endometrioma ablation using plasma energy: retrospective assessment of a 3-year experience. J Minim Invasive Gynecol. 2013;20:573–82. Roman H, Auber M, Mokdad C, Martin C, Diguet A, Marpeau L, Bourdel N. Ovarian endometrioma ablation using plasma energy versus cystectomy: a step toward better preservation of the ovarian parenchyma in women wishing to conceive. Fertil Steril. 2011;96:1396–400. Hart RJ, Hickey M, Maouris P, Buckett W. Excisional surgery versus ablative surgery for ovarian endometriomata. Cochrane Database Syst Rev. 2008;2:CD004992. Alborzi S, Keramati P, Younesi M, Samsami A, Dadras N. The impact of laparoscopic cystectomy on ovarian reserve in patients with unilateral and bilateral endometriomas. Fertil Steril. 2014;101:427–34. Roman H, Bubenheim M, Auber M, Marpeau L, Puscasiu L. Antimullerian hormone level and endometrioma ablation using plasma energy. JSLS. 2014;18:e2014.00002. Pados G, Tsolakidis D, Assimakopoulos E, Athanatos D, Tarlatzis B. Sonographic changes after laparoscopic cystectomy compared with three-stage management in patients with ovarian endometriomas: a prospective randomized study. Hum Reprod. 2010;25:672–7. Donnez J, Lousse JC, Jadoul P, Donnez O, Squifflet J. Laparoscopic management of endometriomas using a combined technique of excisional (cystectomy) and ablative surgery. Fertil Steril. 2010;94:28–32. Li CZ, Wei DY, Wang F, Wang HQ, Yang CR. [Impact on ovarian reserve function by different homostasis methods during laparoscopic cystectomy in treatment of ovarian endometrioma]. Chung-Hua Fu Chan Ko Tsa Chih [Chinese J Obstet Gynecol]. [English Abstract]. 2013;48:11–5. Uğur M, Turan C, Mungan T, Kuşçu E, Senöz S, Ağiş HT, Gökmen O. Endometriosis in association with müllerian anomalies. Gynecol Obstet Investig. 1995;40:261–4. Fedele L, Bianchi S, Di Nola G, Franchi D, Candiani GB. Endometriosis and nonobstructive Müllerian anomalies. Obstet Gynecol. 1992;79:515–7. Olive DL, Henderson DY. Endometriosis and Mullerian anomalies. Obstet Gynecol. 1987;69:412–5. Heinonen P. Unicornuate uterus and rudimentary horn. Fertil Steril. 1997;68:224–30. Spitzer RF, Kives S, Allen LM. Case series of laparoscopically resected noncommunicating functional uterine horns. J Pediatr Adolesc Gynecol. 2009;22:e23–8. Liatasikos A, Tsikouras P, Souftas V, Ammari A, Prassopoulos P, Maroulis G, Liberis V. Diagnosis and laparoscopic management of a rudimentary uterine horn in a teenage girl, presenting with haematometra and severe endometriosis: our experience and review of literature. Minim Invasive Ther Allied Technol. 2010;19:241–7. Gordts S, Puttemans P, Gordts S, Brosens I. Ovarian endometrioma in the adolescent: a plea for early-stage diagnosis and full surgical treatment. Gynecol Surg. 2015;12:21–30. Marsh EE, Laufer MR. Endometriosis in premenarcheal girls who do not have an associated obstructive anomaly. Fertil Steril. 2005;83:758–60. Gogacz M, Sarzynski M, Napierała R, Sierocińska-Sawa J, Semczuk A. Ovarian endometrioma in an 11-year-old girl before menarche: a case study with literature review. J Pediatr Adolesc Gynecol. 2012;25:e5–7. Ebert AD, Fuhr N, David M, Schneppel L, Papadopoulos T. Histological confirmation of endometriosis in a 9-year-old girl suffering from unexplained cyclic pelvic pain since her eighth year of life. Gynecol Obstet Investig. 2009;67:158–61. Tandoi I, Somigliana E, Riparini J, Ronzoni S, Vigano P, Candiani M. High rate of endometriosis recurrence in young women. J Pediatr Adolesc Gynecol. 2011;24:376–9. Ventolini G, Horowitz GM, Long R. Endometriosis in adolescence: a long term follow-up fecundability assessment. Reprod Biol Endocrinol. 2005;3:14–7. Chapron C, Lafay-Pillet MC, Monceau E, et al. Questioning patients about their adolescent history can identify markers associated with deep infiltrating endometriosis. Fertil Steril. 2011;95:877–81. Laufer MR, Sanfillipo J, Rose G. Adolescent endometriosis: diagnosis and treatment approaches. J Pediatr Adolesc Gynecol. 2003;16:S3–S11. Doyle JO, Missmer SA, Laufer MR. The effect of combined surgical medical intervention on the progression of endometriosis in an adolescent and young adult population. J Pediatr Adolesc Gynecol. 2009;22:257–63. Unger CA, Laufer MR. Progression of endometriosis in nonmedically managed adolescents: a case series. J Pediatr Adolesc Gynecol. 2011;24:e21–3. Franke HR, van de Weijer PH, Pennings TM, van der Mooren MJ. Gonadotropin-releasing hormone agonist plus “add-back” hormone replacement therapy for treatment of endometriosis: a prospective, randomized, placebo-controlled, double blind trial. Fertil Steril. 2000;74:534–9. Somigliana E, Vercellini P, Vigano P, Benaglia L, Busnelli A, Fedele L. Postoperative medical therapy after surgical treatment of endometriosis: from adjuvant therapy to tertiary prevention. J Minim Invasive Gynecol. 2014;21:328–34. Yoost J, LaJoie AS, Hertweck P, Loveless M. Use of the levonorgestrel intrauterine system in adolescents with endometriosis. J Pediatr Adolesc Gynecol. 2013;26:120–4. González-Echevarría AM, Rosario E, Acevedo S, Flores I. Impact of coping strategies on quality of life of adolescents and young women with endometriosis. J Psychosom Obstet Gynecol. 2018;0:1–8. Wilson-Harris BM, Nutter B, Falcone T. Long-term fertility after laparoscopy for endometriosis-associated pelvic pain in young adult women. Minim Invasive Gynecol. 2014;21:1061–6. Bai SW, Cho HJ, Kim JY, Jeong KA, Kim SK, Cho DJ, Song CH, Park KH. Endometriosis in an adolescent population: the severance hospital in Korean experience, Yonsei Med J. 2002;43:48–52. Author information Authors and Affiliations Editor information Editors and Affiliations Rights and permissions Copyright information © 2020 Springer Nature Switzerland AG About this chapter Cite this chapter Soriano, D., Bar-Shavit, Y. (2020). Laparoscopic Surgery in Adolescent Endometriosis. In: Nezhat, C.H. (eds) Endometriosis in Adolescents. Springer, Cham. https://doi.org/10.1007/978-3-030-52984-0_36 Download citation DOI: https://doi.org/10.1007/978-3-030-52984-0_36 Published: Publisher Name: Springer, Cham Print ISBN: 978-3-030-52983-3 Online ISBN: 978-3-030-52984-0 eBook Packages: MedicineMedicine (R0)

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